Prince of Wales Clinical School and Neuroscience Research Australia, University of New South Wales, Randwick, Sydney, NSW 2031, Australia.
Clin Neurophysiol. 2011 Dec;122(12):2498-504. doi: 10.1016/j.clinph.2011.04.024. Epub 2011 Jun 2.
To deduce the connectivity underlying ocular vestibular evoked myogenic potentials (OVEMPs) recorded from two sites and produced by lateral transmastoid stimulation in patients with unilateral vestibular dysfunction.
OVEMPs were recorded using lateral impulsive stimuli delivered by a hand-held minishaker placed at the mastoid. Twelve patients were tested using the typical OVEMP recording montage placed inferior to the eyes. In a subset of 6 patients, recordings were also made using a lateral electrode montage. The majority of patients were tested following surgery for inner ear disease. Patient responses were compared to those in normal subjects under similar recording conditions.
For the inferior montage, regardless of which mastoid was stimulated, deficits were observed only from the eye opposite the affected ear. In contrast, OVEMPs recorded using the lateral electrode montage showed changes on both sides.
OVEMPs produced using lateral transmastoid stimulation and recorded from beneath the eyes are generated by a crossed vestibulo-ocular pathway while the projections underlying the lateral responses are likely to be bilateral.
The vestibular-ocular connectivity underlying the OVEMPs recorded from inferior and lateral recording sites differs. For clinical use, the inferior recording site is the simplest to interpret.
推断单侧前庭功能障碍患者经颅外侧刺激记录的双眼前庭眼动肌电位（OVEMPs）的连通性。
使用手持式微型振动器在乳突处施加侧向脉冲刺激记录 OVEMP。12 名患者使用放置在眼睛下方的典型 OVEMP 记录电极进行测试。在 6 名患者的亚组中，还使用外侧电极记录进行记录。大多数患者在内耳疾病手术后接受测试。将患者的反应与相似记录条件下的正常受试者进行比较。
对于下方记录电极，无论刺激哪一侧乳突，仅观察到病变耳对侧眼睛的反应缺失。相比之下，使用外侧电极记录电极记录的 OVEMPs 显示两侧均有变化。
经颅外侧刺激产生并从眼睛下方记录的 OVEMPs 是由交叉前庭眼通路产生的，而外侧反应的投射可能是双侧的。
从下方和外侧记录电极记录的 OVEMPs 的前庭眼连通性不同。对于临床应用，下方记录电极是最简单的解释。
