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经闭孔无张力阴道吊带术治疗女性混合性尿失禁的疗效评价:一年随访结果。

Evaluation of transobturator tension-free vaginal tapes in the management of women with mixed urinary incontinence: one-year outcomes.

机构信息

Division of Applied Health Sciences, School of Medicine and Dentistry, University of Aberdeen, Aberdeen, Scotland, UK.

出版信息

Am J Obstet Gynecol. 2011 Aug;205(2):150.e1-6. doi: 10.1016/j.ajog.2011.03.018. Epub 2011 Mar 16.

Abstract

OBJECTIVE

To assess the efficacy of transobturator tapes in the management of women with urodynamic mixed urinary incontinence (UI).

STUDY DESIGN

A secondary analysis of a prospective randomized study; 83 women with mixed UI on urodynamics and predominant stress UI symptoms were recruited and randomly assigned to undergo "outside-in" or inside-out transobturator tapes. Preoperative assessment included urodynamic assessment and completion of validated symptom severity and quality of life (QoL) questionnaires. The primary outcome was patient-reported success rates at 1-year as assessed by the Patient Global Impression of Improvement (very much/much improved). Secondary outcomes included changes in preoperative urgency/urgency incontinence, changes in QoL scores and comparison between the 2 types of transobturator tapes.

RESULTS

Seventy-seven women completed 1-year follow-up (outside-in [n=42] vs inside-out [n=35]). The patient-reported success rate and objective cure rate were 75% and 90%, respectively. At 1-year follow-up; 40 women (52%) and 31 women (57.4%) reported cure in their preoperative urgency and urgency incontinence, respectively. A total of 74% reported≥10 point improvement in QoL scores.

CONCLUSION

In women with urodynamic mixed incontinence and predominant stress UI, transobturator tapes were associated with good patient-reported success rate at 1 year. Urgency/ urgency incontinence are cured in over 50% of women.

摘要

目的

评估经闭孔吊带术治疗女性动力性混合性尿失禁(UI)的疗效。

研究设计

一项前瞻性随机研究的二次分析;招募了 83 名尿动力学检查显示混合性 UI 且以压力性 UI 症状为主的女性,并将其随机分为“外-内”或“内-外”经闭孔吊带术。术前评估包括尿动力学评估和完成经过验证的症状严重程度和生活质量(QoL)问卷。主要结局是通过患者总体改善印象(非常/明显改善)评估的 1 年时患者报告的成功率。次要结局包括术前急迫/急迫性尿失禁的变化、QoL 评分的变化以及两种经闭孔吊带术的比较。

结果

77 名女性完成了 1 年随访(外-内[42 名] vs 内-外[35 名])。患者报告的成功率和客观治愈率分别为 75%和 90%。1 年随访时,分别有 40 名女性(52%)和 31 名女性(57.4%)报告其术前急迫性和急迫性尿失禁治愈。共有 74%的女性报告 QoL 评分至少提高了 10 分。

结论

在尿动力学检查显示混合性 UI 且以压力性 UI 症状为主的女性中,经闭孔吊带术在 1 年内与良好的患者报告成功率相关。超过 50%的女性急迫性/急迫性尿失禁得到治愈。

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