Wood D P, Kay R, Norris D
Department of Urology, Cleveland Clinic Foundation, Ohio.
Urology. 1990 Jul;36(1):73-8. doi: 10.1016/0090-4295(90)80318-h.
Renal sarcomas in infants and children are extremely uncommon. Previously classified as Wilms tumors with unfavorable histology, these tumors were thought to be variants of Wilms tumors but in general have a worse prognosis. Our recent experience with 4 cases of renal sarcomas indicate that these tumors must be approached individually and treated appropriately. Their histologic picture and their varying response to surgery and chemotherapy suggest that these unusual tumors are not variants of Wilms tumors but instead sarcomas unrelated to the classic Wilms tumors.
婴儿和儿童肾肉瘤极为罕见。这些肿瘤以前被归类为组织学表现不佳的肾母细胞瘤,曾被认为是肾母细胞瘤的变体,但总体预后较差。我们最近对4例肾肉瘤的经验表明,必须对这些肿瘤进行个体化处理并给予适当治疗。它们的组织学特征以及对手术和化疗的不同反应表明,这些不寻常的肿瘤并非肾母细胞瘤的变体,而是与经典肾母细胞瘤无关的肉瘤。