Health Services Research Centre, Akershus University Hospital, Lørenskog, Norway.
Acta Obstet Gynecol Scand. 2011 Nov;90(11):1267-73. doi: 10.1111/j.1600-0412.2011.01204.x. Epub 2011 Jul 18.
To assess the association between maternal emotional distress in pregnancy and delivery of a small-for-gestational age offspring.
A cohort study in pregnancy.
Fifty hospitals with a maternity ward in Norway during 1998-2008.
Seventy-one thousand eight hundred and ninety-eight women with a singleton pregnancy in the Norwegian Mother and Child Cohort Study were followed from early pregnancy to delivery.
Information on presence of emotional distress was obtained through self-administered questionnaires in pregnancy weeks 17 and 30 and on birthweight, gestational length at delivery and sex by linkage to the Medical Birth Registry of Norway. Emotional distress was measured by short forms of the Hopkins Symptom Checklist-25.
Small-for-gestational age offspring (birthweight <2.5th percentile).
Being emotionally distressed at gestational weeks 17 and 30 was not significantly associated with subsequent delivery of a small-for-gestational age infant (adjusted odds ratio 1.16; 95% confidence interval 0.87-1.54). This estimate was adjusted for smoking in pregnancy, parity, diabetes, pre-eclampsia, body mass index, education and maternal age.
Emotional distress during pregnancy was not associated with subsequent delivery of a small-for-gestational age infant.
评估妊娠期间产妇情绪困扰与胎儿小于胎龄儿之间的关系。
妊娠队列研究。
1998-2008 年期间挪威 50 家有妇产科病房的医院。
挪威母婴队列研究中，71898 名单胎妊娠的妇女从早孕开始一直随访到分娩。
通过妊娠 17 周和 30 周的自我管理问卷、与挪威医学出生登记处的链接获得情绪困扰的存在信息，通过霍普金斯症状清单 25 短表来衡量情绪困扰。
小于胎龄儿（出生体重<第 2.5 百分位数）。
妊娠 17 周和 30 周时情绪困扰与随后小于胎龄儿的分娩无显著相关性（调整后的优势比 1.16；95%置信区间 0.87-1.54）。这一估计值是根据妊娠期间吸烟、产次、糖尿病、子痫前期、体重指数、教育程度和母亲年龄进行调整的。
妊娠期间的情绪困扰与随后的小于胎龄儿分娩无关。
