Department of Microbiology, Chittagong Veterinary and Animal Sciences University, Khulshi, Bangladesh.
Transbound Emerg Dis. 2011 Dec;58(6):519-25. doi: 10.1111/j.1865-1682.2011.01235.x. Epub 2011 Jun 6.
Small-scale commercial chicken farms (FAO-defined system 3) with poor biosecurity predominate in developing countries including Bangladesh. By enroling fifteen highly pathogenic avian influenza (HPAI) cases occurring in such farms - (February - April 2008) and 45 control farms (March-May 2008) with similar set up, we conducted a case-control study to evaluate the risk factors associated with HPAI H5N1 virus infections in chickens reared in small-scale commercial farms in a spatially high-risk area in Bangladesh. Data collected by a questionnaire from the selected farms were analysed by univariable analysis and multivariable conditional logistic regression. The risk factors independently associated were 'dead crow seen at or near farm' [odds ratio (OR) 47.4, 95% confidence interval (CI) 4.7-480.3, P = 0.001], 'exchanging eggtrays with market vendors' (OR 20.4, 95% CI 1.9-225.5, P = 0.014) and 'mortality seen in backyard chicken reared nearby' (OR 19.4, 95% CI 2.8-131.9, P = 0.002). These observations suggest that improved biosecurity might reduce the occurrence of HPAI outbreaks in small-scale commercial farms in Bangladesh.
小规模商业性养鸡场（粮农组织定义的系统 3）在包括孟加拉国在内的发展中国家普遍存在生物安全措施较差的情况。我们通过登记发生在这些农场中的 15 起高致病性禽流感（HPAI）病例（2008 年 2 月至 4 月）和 45 个对照农场（2008 年 3 月至 5 月），这些农场的设置类似，开展了一项病例对照研究，以评估在孟加拉国空间高风险地区小规模商业性农场饲养的鸡中与 HPAI H5N1 病毒感染相关的风险因素。通过从选定农场收集的问卷收集的数据，通过单变量分析和多变量条件逻辑回归进行分析。独立相关的风险因素是“在农场或附近看到死乌鸦”[比值比（OR）47.4，95%置信区间（CI）4.7-480.3，P = 0.001]、“与市场摊贩交换蛋盘”（OR 20.4，95%CI 1.9-225.5，P = 0.014）和“附近后院鸡的死亡率”（OR 19.4，95%CI 2.8-131.9，P = 0.002）。这些观察结果表明，加强生物安全措施可能会降低孟加拉国小规模商业性养鸡场中 HPAI 暴发的发生。
