Department of Chemistry, Seoul National University, Seoul 151-747, Korea.
Chem Commun (Camb). 2011 Jul 21;47(27):7734-6. doi: 10.1039/c1cc12618k. Epub 2011 Jun 7.
In this communication, we report that 9-aryl-1,2-dihydropyrrolo[3,4-b]indolizin-3-one (Seoul-Fluor) can serve as a potential platform for colorful ratiometric fluorescent pH sensors by simple incorporation of pH responsive elements on Seoul-Fluor. Seoul-Fluor-based fluorescent pH sensors allow the emission- and pH-tuning ability upon protonation by varying their pK(a) values and electronic characteristics of substituents by a rational design.
在本通讯中，我们报告了 9-芳基-1,2-二氢吡咯并[3,4-b]吲哚啉-3-酮（首尔荧光素）可以通过在首尔荧光素上简单地加入 pH 响应基团，作为一种潜在的用于多彩比率荧光 pH 传感器的平台。基于首尔荧光素的荧光 pH 传感器通过合理设计改变其 pK(a) 值和取代基的电子特性，可以在质子化时通过调节发射和 pH 值来实现。
