Lalitha V S, Rubinstein L J
Cancer. 1979 Jan;43(1):246-57. doi: 10.1002/1097-0142(197901)43:1<246::aid-cncr2820430136>3.0.co;2-j.
The clinicopathologic features of eight new cases of combined intracranial sarcoma and glioma are described. This type of mixed cerebral tumor is histologically characterized by a peripheral distribution of the gliomatous elements in relation to a more centrally situated meningeal or intracerebral sarcoma, and by the frequent presence of gradual transitions from reactive to frankly neoplastic astrocytes. In six of the eight cases, the additional development of either infiltrating astrocytoma or frank glioblastoma in the adjacent brain was demonstrated; this was interpreted as a further expression of malignant glial reaction. It is suggested that these tumors be termed "sarcogliomas" to distinguish them from the type of mixed glioma and sarcoma that has recently been redesignated "gliosarcoma."
本文描述了8例新的颅内肉瘤合并胶质瘤病例的临床病理特征。这种类型的混合性脑肿瘤在组织学上的特征是，胶质瘤成分呈外周分布，相对更位于中央的脑膜或脑内肉瘤，以及经常出现从反应性星形胶质细胞到明显肿瘤性星形胶质细胞的逐渐过渡。在8例病例中的6例中，显示相邻脑内有浸润性星形细胞瘤或明显的胶质母细胞瘤进一步发展；这被解释为恶性胶质反应的进一步表现。建议将这些肿瘤称为“肉瘤胶质瘤”，以将它们与最近重新命名为“胶质肉瘤”的混合性胶质瘤和肉瘤类型区分开来。
