Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany.
Stem Cells. 2011 Aug;29(8):1165-9. doi: 10.1002/stem.669.
Several research groups have claimed to have successfully generated pluripotent or multipotent cells from human testis. However, the pluripotent character of those cells with respect to gene expression profile and ability to generate teratomas has been called into question. Here, we critically review these reports and provide insight to guide future studies on the derivation of human pluripotent cells from testicular tissue.
一些研究小组声称已经成功地从人类睾丸中产生了多能或多能细胞。然而，这些细胞在基因表达谱和生成畸胎瘤的能力方面的多能特性已受到质疑。在这里，我们批判性地回顾这些报告，并提供见解以指导未来从睾丸组织中获得人类多能细胞的研究。
