Baccelli G, Albertini R, Mancia G, Zanchetti A
Cardiovasc Res. 1978 Sep;12(9):523-8. doi: 10.1093/cvr/12.9.523.
In the intact cat desynchronised sleep induces arterial hypotension and mesenteric vasodilatation, whereas in limb muscles vasoconstriction occurs because of the concurrent action of a spinal vasoconstriction reflex. After sino-aortic denervation arterial hypotension is exaggerated and mesenteric vasodilatation is greater, while the muscular bed of the limbs also becomes vasodilated rather than constricted. It is concluded that during desynchronised sleep the sino-aortic afferents act to check a central influence inhibiting vasoconstrictor tone both in the viscera and muscles: thus an excessive fall in blood pressure is prevented by avoiding a too large visceral vasodilatation and by unmasking the vasoconstrictor action of the spinal reflex in the limbs.
在完整无损的猫身上，去同步化睡眠会导致动脉血压降低和肠系膜血管舒张，而在肢体肌肉中，由于脊髓血管收缩反射的同时作用，会发生血管收缩。在进行窦主动脉去神经支配后，动脉血压降低的情况会加剧，肠系膜血管舒张也更明显，同时肢体的肌肉床也会变成血管舒张而非收缩。得出的结论是，在去同步化睡眠期间，窦主动脉传入神经起到抑制内脏和肌肉中血管收缩张力的中枢影响的作用：因此，通过避免内脏血管过度舒张以及通过揭示肢体中脊髓反射的血管收缩作用，可防止血压过度下降。
