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全球 10-24 岁年轻人疾病负担的系统分析

Global burden of disease in young people aged 10-24 years: a systematic analysis.

机构信息

Department of Health Statistics and Informatics, WHO, Geneva, Switzerland.

出版信息

Lancet. 2011 Jun 18;377(9783):2093-102. doi: 10.1016/S0140-6736(11)60512-6. Epub 2011 Jun 7.

DOI:10.1016/S0140-6736(11)60512-6
PMID:21652063
Abstract

BACKGROUND

Young people aged 10-24 years represent 27% of the world's population. Although important health problems and risk factors for disease in later life emerge in these years, the contribution to the global burden of disease is unknown. We describe the global burden of disease arising in young people and the contribution of risk factors to that burden.

METHODS

We used data from WHO's 2004 Global Burden of Disease study. Cause-specific disability-adjusted life-years (DALYs) for young people aged 10-24 years were estimated by WHO region on the basis of available data for incidence, prevalence, severity, and mortality. WHO member states were classified into low-income, middle-income, and high-income countries, and into WHO regions. We estimated DALYs attributable to specific global health risk factors using the comparative risk assessment method. DALYs were divided into years of life lost because of premature mortality (YLLs) and years lost because of disability (YLDs), and are presented for regions by sex and by 5-year age groups.

FINDINGS

The total number of incident DALYs in those aged 10-24 years was about 236 million, representing 15·5% of total DALYs for all age groups. Africa had the highest rate of DALYs for this age group, which was 2·5 times greater than in high-income countries (208 vs 82 DALYs per 1000 population). Across regions, DALY rates were 12% higher in girls than in boys between 15 and 19 years (137 vs 153). Worldwide, the three main causes of YLDs for 10-24-year-olds were neuropsychiatric disorders (45%), unintentional injuries (12%), and infectious and parasitic diseases (10%). The main risk factors for incident DALYs in 10-24-year-olds were alcohol (7% of DALYs), unsafe sex (4%), iron deficiency (3%), lack of contraception (2%), and illicit drug use (2%).

INTERPRETATION

The health of young people has been largely neglected in global public health because this age group is perceived as healthy. However, opportunities for prevention of disease and injury in this age group are not fully exploited. The findings from this study suggest that adolescent health would benefit from increased public health attention.

FUNDING

None.

摘要

背景

10-24 岁的年轻人占世界人口的 27%。尽管在这几年中出现了重要的健康问题和晚年疾病的风险因素,但它们对全球疾病负担的贡献尚不清楚。我们描述了年轻人的全球疾病负担以及这些风险因素对疾病负担的影响。

方法

我们使用了世卫组织 2004 年全球疾病负担研究的数据。根据发病率、患病率、严重程度和死亡率的现有数据,按世卫组织区域估算了 10-24 岁年轻人的特定病因残疾调整生命年(DALY)。世卫组织成员国被分为低收入、中等收入和高收入国家,并分为世卫组织区域。我们使用比较风险评估方法估算了特定全球健康风险因素造成的 DALY。DALY 分为因过早死亡而损失的生命年(YLL)和因残疾而损失的生命年(YLD),并按性别和 5 岁年龄组呈现给各区域。

结果

10-24 岁人群新发 DALY 总数约为 2.36 亿,占所有年龄组 DALY 的 15.5%。非洲该年龄组的 DALY 率最高,是高收入国家的 2.5 倍(每 1000 人 208 与 82)。在各区域,15-19 岁女孩的 DALY 率比男孩高 12%(137 与 153)。全世界,10-24 岁人群 YLD 的三个主要原因是神经精神障碍(45%)、意外伤害(12%)和感染性及寄生虫病(10%)。10-24 岁人群新发 DALY 的主要风险因素是酒精(占 DALY 的 7%)、不安全的性行为(4%)、缺铁(3%)、缺乏避孕措施(2%)和非法药物使用(2%)。

解释

全球公共卫生在很大程度上忽视了年轻人的健康,因为人们认为这个年龄段的人是健康的。然而,这个年龄段的疾病和伤害预防机会并没有得到充分利用。本研究的结果表明,青少年健康将受益于更多的公共卫生关注。

资金

无。

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