Rubie H, Assouline C, Prere M F, Dutour A, Lemozy J, Mouls J L, Gayet-Mengelle C, Robert A
Médecine infantile B, CHU Purpan, Toulouse, France.
Pediatrie. 1990;45(5):333-8.
The authors report the infectious complications observed during the treatment of acute lymphoblastic leukemia in 70 children, followed by a same team, with the same protocole, for a period of 6 years (mean follow-up: 42.3 months). The complications were mainly bacterial during induction phase, mainly staphylococcic the microbiological follow-up and a rapid empiric antibiotic therapy allowed to control more than 80% of the febrile episodes. There was one death from fulminant pyocyanic infection.
作者报告了由同一团队采用相同方案，对70名儿童急性淋巴细胞白血病进行为期6年（平均随访42.3个月）治疗期间观察到的感染性并发症。在诱导期并发症主要为细菌性，微生物学随访显示主要为葡萄球菌感染，快速经验性抗生素治疗控制了超过80%的发热性发作。有1例死于暴发性绿脓杆菌感染。
