Naylor B
Department of Pathology, University of Michigan, Ann Arbor.
Acta Cytol. 1990 Jul-Aug;34(4):474-8.
Curschmann's spirals were found in smears and cell block preparations of five spontaneously occurring pleural and peritoneal fluids. The spirals were similar to those seen in the respiratory tract, although generally much smaller. In three of the five cases, the fluids also contained mucus-secreting adenocarcinoma cells; it is postulated that the spirals formed from mucus secreted by these cells. In the other two cases, there was evidence of serosal inflammation; it is suggested that the spirals in these cases developed from submesothelial connective tissue mucosubstances that entered the serosal cavity through a mesothelium of increased permeability due to the inflammation. No simple explanation can be accepted as to the exact mode of spiral formation, which is presumed to be a complex physical and biochemical phenomenon.
在5份自发性胸腔和腹腔积液的涂片及细胞块标本中发现了库施曼螺旋体。这些螺旋体与呼吸道中所见的相似，尽管通常要小得多。在5例中的3例中，积液还含有分泌黏液的腺癌细胞；据推测，这些螺旋体是由这些细胞分泌的黏液形成的。在另外2例中，有浆膜炎症的证据；提示这些病例中的螺旋体是由间皮下结缔组织黏液物质形成的，这些物质通过因炎症而通透性增加的间皮进入浆膜腔。关于螺旋体形成的确切方式，尚无简单的解释能被接受，推测这是一个复杂的物理和生化现象。
