Dimri Goberdhan P
Department of Medicine, ENH Research Institute, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Evanston, IL 60201.
Breast Cancer (Auckl). 2008;1:1-5. Epub 2008 Jan 15.
I would like to welcome breast cancer research community to the first editorial of our newest journal "Breast Cancer: Basic and Clinical Research". In pursuit of breast cancer culprits, we have come a long way since the early 90's when the first breast cancer susceptibility gene BRCA1 was mapped and cloned. In the past few years, several new loci associated with the various degree of breast cancer risk have been identified using "Candidate Gene Association Study (CGAS) and Genome-Wide Association Study (GWAS)" approaches. This editorial is meant to quickly glance over recent findings of these population-based association studies.
我谨代表乳腺癌研究领域，欢迎大家阅读我们最新期刊《乳腺癌：基础与临床研究》的首篇社论。自90年代初首个乳腺癌易感基因BRCA1被定位和克隆以来，在寻找乳腺癌病因的道路上我们已经取得了长足的进展。在过去几年中，通过“候选基因关联研究（CGAS）”和“全基因组关联研究（GWAS）”方法，已经确定了几个与不同程度乳腺癌风险相关的新基因座。这篇社论旨在快速浏览这些基于人群的关联研究的最新发现。
