Department of Obstetrics and Gynaecology, Division Woman and Child, University Hospital Gasthuisberg, Leuven, Belgium.
Prenat Diagn. 2011 Jul;31(7):661-6. doi: 10.1002/pd.2780. Epub 2011 Jun 8.
With the increased use of invasive fetal procedures, the number of women facing post-procedure membrane rupture is increasing. Here we review the use of platelets and fresh frozen plasma for sealing iatrogenic fetal membrane defects by describing the mechanisms of action of the amniopatch procedure as well as published experience. In cases of iatrogenic preterm pre-labour rupture of the membranes, amniopatch effectively seals the fetal membranes in over two-thirds of cases. There is a risk of 16% of in utero fetal death, which may occur at varying intervals from the procedure and often for unknown reasons. Amniopatch has also been used as a treatment of chorionic membrane separation. In summary, current experience suggests that in cases of early onset but persistent amniotic fluid leakage following an invasive fetal procedure, amniopatch is an option.
随着侵入性胎儿手术的增加，面临术后胎膜破裂的女性人数正在增加。在这里，我们通过描述羊膜片修补术的作用机制以及已发表的经验，来回顾血小板和新鲜冷冻血浆在封闭医源性胎膜缺陷中的应用。在医源性早产胎膜早破的情况下，羊膜片在超过三分之二的情况下有效地封闭了胎膜。有 16%的胎儿在宫内死亡的风险，这可能在不同的时间间隔内发生，而且往往原因不明。羊膜片也被用于治疗绒毛膜膜分离。总之，目前的经验表明，在侵入性胎儿手术后出现早期但持续的羊水渗漏的情况下，羊膜片是一种选择。
