Division of Clinical Research/Infectious Diseases, National Health Research Institutes, Zhunan, Miaoli County 350, Taiwan.
Diagn Microbiol Infect Dis. 2011 Aug;70(4):528-30. doi: 10.1016/j.diagmicrobio.2011.04.003. Epub 2011 Jun 11.
The serologic markers of the therapeutic response of chronic necrotizing pulmonary aspergillosis (CNPA) are rarely reported. Here, we describe the changes in galactomannan (GM) antigenemia in a patient receiving oral voriconazole for CNPA, in whom a resolution of GM antigenemia to a normal level was associated with clinical improvements. The serum GM index can be an adjunctive tool for the diagnosis and monitoring of the therapeutic response of CNPA.
慢性坏死性肺曲霉病(CNPA)治疗反应的血清学标志物很少有报道。在这里,我们描述了一名接受口服伏立康唑治疗 CNPA 的患者中半乳甘露聚糖(GM)抗原血症的变化,GM 抗原血症恢复正常水平与临床改善相关。血清 GM 指数可作为辅助诊断和监测 CNPA 治疗反应的工具。