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口服伏立康唑治疗慢性坏死性肺曲霉病患者中半乳甘露聚糖抗原血症的消退。

Resolution of galactomannan antigenemia in a patient receiving oral voriconazole for chronic necrotizing pulmonary aspergillosis.

机构信息

Division of Clinical Research/Infectious Diseases, National Health Research Institutes, Zhunan, Miaoli County 350, Taiwan.

出版信息

Diagn Microbiol Infect Dis. 2011 Aug;70(4):528-30. doi: 10.1016/j.diagmicrobio.2011.04.003. Epub 2011 Jun 11.

DOI:10.1016/j.diagmicrobio.2011.04.003
PMID:21658879
Abstract

The serologic markers of the therapeutic response of chronic necrotizing pulmonary aspergillosis (CNPA) are rarely reported. Here, we describe the changes in galactomannan (GM) antigenemia in a patient receiving oral voriconazole for CNPA, in whom a resolution of GM antigenemia to a normal level was associated with clinical improvements. The serum GM index can be an adjunctive tool for the diagnosis and monitoring of the therapeutic response of CNPA.

摘要

慢性坏死性肺曲霉病(CNPA)治疗反应的血清学标志物很少有报道。在这里,我们描述了一名接受口服伏立康唑治疗 CNPA 的患者中半乳甘露聚糖(GM)抗原血症的变化,GM 抗原血症恢复正常水平与临床改善相关。血清 GM 指数可作为辅助诊断和监测 CNPA 治疗反应的工具。

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Resolution of galactomannan antigenemia in a patient receiving oral voriconazole for chronic necrotizing pulmonary aspergillosis.口服伏立康唑治疗慢性坏死性肺曲霉病患者中半乳甘露聚糖抗原血症的消退。
Diagn Microbiol Infect Dis. 2011 Aug;70(4):528-30. doi: 10.1016/j.diagmicrobio.2011.04.003. Epub 2011 Jun 11.
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