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心源性和主动脉源性脑栓塞的左右倾向和病变模式。

Right-left propensity and lesion patterns between cardiogenic and aortogenic cerebral embolisms.

机构信息

Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, South Korea.

出版信息

Stroke. 2011 Aug;42(8):2323-5. doi: 10.1161/STROKEAHA.111.616573. Epub 2011 Jun 9.

DOI:10.1161/STROKEAHA.111.616573
PMID:21659640
Abstract

BACKGROUND AND PURPOSE

Based on thrombus location and nature and anatomic features of aorta and cerebral arteries, we hypothesized that cardiogenic embolisms (CE) and aortogenic embolisms (AE) might have different right-left propensity and lesion patterns.

METHODS

We retrospectively reviewed patients with acute ischemic stroke with high-risk CE sources or moderate-or-severe aortic atherosclerotic plaques on transesophageal echocardiography. Lesion side and patterns on diffusion-weighted imaging were compared between CE and AE.

RESULTS

CE was identified in 123 and AE in 63. In multivariate analysis, right-sided lesions and corticosubcortical infarcts were independently associated with CE, and left-sided lesions and pial infarcts were independently associated with AE.

CONCLUSIONS

CE and AE have different radiological characteristics, as shown by the right-left propensity and lesions patterns of cerebral infarcts.

摘要

背景与目的

基于血栓位置和性质以及主动脉和脑动脉的解剖学特征,我们推测心源性栓塞(CE)和主动脉源性栓塞(AE)可能具有不同的左右倾向和病变模式。

方法

我们回顾性分析了经食管超声心动图检查显示有高风险 CE 源或中重度主动脉粥样硬化斑块的急性缺血性脑卒中患者。比较了 CE 和 AE 之间弥散加权成像上的病变侧和病变模式。

结果

CE 组 123 例,AE 组 63 例。多变量分析显示,右侧病变和皮质下梗死与 CE 独立相关,左侧病变和软脑膜梗死与 AE 独立相关。

结论

CE 和 AE 具有不同的影像学特征,表现为脑梗死的左右倾向和病变模式。

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