Stojković Ana, Boras Vanja Vucićević, Planbak Darije, Lisić Miroslav, Srdjak Srećko
University of Zagreb, School of Dental Medicine, Department of Periodontology, Zagreb, Croatia.
Coll Antropol. 2011 Mar;35(1):67-71.
A number of periodontal changes have been associated with human immunodeficiency virus (HIV) infection, however our knowledge of the epidemiology, microbiology, host response and natural history of these conditions remains limited. Therefore, the aim of our study was the assessment of possible differences in periodontal status of HIV infected subjects when compared with healthy controls matched for age, gender and smoking habit in Croatian population. Assessment included measurement of plaque accumulation using approximal plaque index, measurement of gingival inflammation by use of sulcus bleeding index, pocket depth, gingival recession as well as the number of decayed, missing and filled teeth in 25 HIV infected subjects (age range 22-61, X = 40.8 years) in comparison with 25 healthy controls (age range 20-62, X = 40.9 years). Statistical analysis was performed by use of descriptive statistics and Mann-Whitney U test showed significantly increased level of inflammation of the marginal gingiva in HIV infected subjects when compared to the controls (p < 0.002). Significantly increased mean values of periodontal pockets (p < 0.002) and the deepest periodontal pocket (p < 0.003) were also observed when HIV infected subjects were compared to the healthy controls. In HIV infected subjects there was significant increase in the number of decayed, missing and decrease in the number of filled teeth (p < 0.002; p < 0.002; p < 0.009, respectively). The results of this study once again highlight the need for more prevalent periodontal check-ups and treatments in HIV infected subjects.
许多牙周变化都与人类免疫缺陷病毒（HIV）感染有关，然而，我们对这些病症的流行病学、微生物学、宿主反应及自然病史的了解仍然有限。因此，我们研究的目的是评估在克罗地亚人群中，与年龄匹配、性别相同且吸烟习惯一致的健康对照相比，HIV感染受试者的牙周状况可能存在的差异。评估内容包括使用邻面菌斑指数测量菌斑堆积情况，使用龈沟出血指数测量牙龈炎症，测量牙周袋深度、牙龈退缩情况，以及统计25名HIV感染受试者（年龄范围22 - 61岁，X = 40.8岁）和25名健康对照（年龄范围20 - 62岁，X = 40.9岁）的龋失补牙数。通过描述性统计进行数据分析，Mann - Whitney U检验显示，与对照组相比，HIV感染受试者的边缘龈炎症水平显著升高（p < 0.002）。与健康对照相比，HIV感染受试者的牙周袋平均深度（p < 0.002）和最深牙周袋深度（p < 0.003）也显著增加。在HIV感染受试者中，龋失牙数显著增加，补牙数减少（分别为p < 0.002；p < 0.002；p < 0.009）。本研究结果再次凸显了对HIV感染受试者进行更普遍的牙周检查和治疗的必要性。
