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[1999年至2007年期间塞哥维亚地区普通人群的抗生素消费情况]

[Consumption of antibiotics of the general population of Segovia area during the period between 1999 to 2007].

作者信息

Pinilla Sánchez José Maria, Eiros Bouza José Maria, Arahuetes Benito Fuencisla, Vega Quiroga Saturio, Moreno Sánchez Elena

机构信息

Gerencia de Atención Primaria de Segovia, Santo Tomás, 9, 40002 Segovia.

出版信息

Rev Esp Quimioter. 2011 Jun;24(2):99-106.

Abstract

INTRODUCTION

The antibiotics are the medicaments most used after the analgesics, being prescribed more than 85 % in Primary Care. The aim of the study is to analyze the evolution of the prescription of antibiotics of systemic use in the general population of the Area of Segovia, during the years 1999-2007 and to know his trends evolution.

MATERIAL AND METHODS

Antibiotics prescribed to the general population on the part of the Family physicians were processed using the information system of drugstore "CONCYLIA" that supplies the information in the shape of defined daily dose (DDD), transformed later into the indicator DHD (DDD for 1.000 inhabitants per day) taking as a base the population information of sanitary card.

RESULTS

The global prescription of antibiotics of systemic use was high, 18,06 DHD (IC:17,22-18,90), with a variable evolution along the study in the shape of basin of low concavity. The percentage of prescription of penicillins was 64.42 % of the total of prescriptions corresponding to the group J01.

CONCLUSIONS

The prescription in the Area of Segovia has presented a contained consumption in relation to other studies, showing differences in the volume of prescription from each the subgroups. The centralization of the consumption emphasizes in the subgroup of penicillins that supposed almost two third parts of the prescribed DDD. A change in the habits of prescription is observed detailing a decrease of the amoxicillin use and an increase of amoxicillin-clavulanic acid.

摘要

引言

抗生素是仅次于镇痛药使用最为广泛的药物,在初级医疗保健中其处方量超过85%。本研究旨在分析1999年至2007年期间塞哥维亚地区普通人群全身用抗生素的处方演变情况,并了解其趋势变化。

材料与方法

利用药店信息系统“CONCYLIA”处理家庭医生为普通人群开具的抗生素处方,该系统以限定日剂量(DDD)的形式提供信息,随后以卫生卡中的人口信息为基础,将其转换为指标DHD(每日每千居民的DDD)。

结果

全身用抗生素的总体处方量较高,为18.06 DHD(95%置信区间:17.22 - 18.90),在研究期间呈低凹形盆地状的变化趋势。青霉素类药物的处方占比为J01组总处方量的64.42%。

结论

与其他研究相比,塞哥维亚地区的抗生素处方量相对较低,各亚组的处方量存在差异。消费集中在青霉素亚组,该亚组的DDD处方量几乎占三分之二。观察到处方习惯的变化,具体表现为阿莫西林的使用量减少,而阿莫西林 - 克拉维酸的使用量增加。

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