International Health Care Center, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Hepatobiliary Pancreat Dis Int. 2011 Jun;10(3):276-9. doi: 10.1016/s1499-3872(11)60046-5.
Fatty liver is a common chronic liver disease worldwide. It is associated with an increasing morbidity in China in recent years. The aim of this study was to analyze the effect of drinking alcohol on the hemoglobin and biochemical values of patients with fatty liver.
We investigated the clinical and laboratory data of 669 patients with fatty liver. Of the 669 patients, 166 consumed alcohol more than 60 g per week for at least 2 years, and 503 did not have a history of long-term alcohol consumption. We further analyzed the relationship between alcohol consumption and clinical characteristics of these patients.
The values of aspartate transaminase (AST), gamma-glutamyl transpeptidase (GGT), and hemoglobin in the long-term consumption group were significantly higher than those in the non long-term consumption group (P<0.05). In the patients without long-term alcohol consumption, the values of GGT and hemoglobin in patients with light alcohol consumption were significantly higher than those in non alcohol consumers (P<0.05).
Alcohol consumption is associated with significantly increased values of AST, GGT, and hemoglobin in patients with fatty liver, suggesting their potential roles in hepatic steatosis.
脂肪肝是一种常见的慢性肝病，在全球范围内普遍存在。近年来，中国的脂肪肝发病率呈上升趋势。本研究旨在分析饮酒对脂肪肝患者血红蛋白和生化指标的影响。
我们调查了 669 例脂肪肝患者的临床和实验室数据。在这 669 例患者中，166 例患者每周饮酒超过 60 克，且至少持续 2 年，503 例患者无长期饮酒史。我们进一步分析了饮酒与这些患者临床特征之间的关系。
长期饮酒组的天冬氨酸转氨酶（AST）、γ-谷氨酰转肽酶（GGT）和血红蛋白值明显高于非长期饮酒组（P<0.05）。在无长期饮酒史的患者中，轻度饮酒患者的 GGT 和血红蛋白值明显高于非饮酒者（P<0.05）。
饮酒与脂肪肝患者 AST、GGT 和血红蛋白值显著升高有关，提示其在肝脂肪变性中可能具有一定作用。
