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[实验性沙门氏菌感染中的脂质过氧化作用]

[Lipid peroxidation in experimental Salmonella infection].

作者信息

Martynenko L D, Shepeleva A P, Simovan'ian E N, Zemliankina L P, Aleshukina A V, Smykova G I, Savis'ko A A, Dmitrieva N A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1990 Apr(4):7-11.

PMID:2166987
Abstract

The results of investigation of lipid peroxidation in experimental Salmonella infection in 21-day-old rabbits are analyzed. Salmonella infection was accompanied by activation of lipid peroxidation not only in enterocytes, but also in blood serum. An increase in the level of malonic dialdehyde leads to a decrease in the antioxidation capacity and in the peroxidation resistance of erythrocytic membranes. The severity of the pathological process was found related to the activity of lipid peroxidation.

摘要

分析了对21日龄家兔实验性沙门氏菌感染中脂质过氧化的调查结果。沙门氏菌感染不仅伴随着肠细胞中脂质过氧化的激活,也伴随着血清中脂质过氧化的激活。丙二醛水平的升高导致红细胞膜抗氧化能力和抗过氧化能力的下降。发现病理过程的严重程度与脂质过氧化的活性有关。

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