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[肾脏病学中的抗生素治疗]

[Antibiotic therapy in nephrology].

作者信息

Niemczyk Stanisław

机构信息

Wojskowy Instytut Medyczny w Warszawie, Klinika Chorób Wewnetrznych, Nefrologii i Dializoterapii, CSK MON.

出版信息

Pol Merkur Lekarski. 2011 May;30(179):342-5.

Abstract

The use of antibiotics in patients with kidney diseases is associated mainly with urinary tract infections (UTI) and urosepsis. Treatment of bacterial infections not related to UTI in patients with chronic renal failure is usually more complicated than in subjects with normal renal function. The high incidence of UTI, recurrent and chronic character of these disorders make them difficult to cure. In all these situations it is important to use effective drugs, without nephrotoxicity, with minimal risk of building up the resistance. Due to the increasing number of dialysis patients, especially treated with hemodialysis, it becomes essential to use effective antibacterial therapy in this group of patients, including infections specific for this kind of treatment. Proper mode of treatment adjusted to type of renal replacement therapy (hemodialysis, peritoneal dialysis or continuous renal replacement therapy) is very important.

摘要

肾病患者使用抗生素主要与尿路感染(UTI)和尿脓毒症有关。慢性肾衰竭患者中与UTI无关的细菌感染治疗通常比肾功能正常的患者更为复杂。UTI的高发病率、这些疾病的复发性和慢性特征使其难以治愈。在所有这些情况下,使用有效的、无肾毒性且耐药风险最小的药物非常重要。由于透析患者数量不断增加,尤其是接受血液透析治疗的患者,对这组患者使用有效的抗菌治疗变得至关重要,包括针对此类治疗的特定感染。根据肾脏替代治疗类型(血液透析、腹膜透析或连续性肾脏替代治疗)调整适当的治疗方式非常重要。

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