Maksimov V F, Korostyshevskaia I M
Ross Fiziol Zh Im I M Sechenova. 2011 Mar;97(3):263-75.
Classic and modern data on natriuretic peptide hormones that are synthesized in cardiac atria and participate in hemodynamic and water-salt balance regulation are summarized in this paper. Cumulated data on polypeptide variety, their structure, intracellular syntheses, physiological effects and concentration alterations during model experiments and cardiovascular pathology are presented. Unsolved problems including methods of plasma peptides concentration measurements, their role in heart failure development, and their clinical significance are discussed.
本文总结了关于在心房合成并参与血流动力学和水盐平衡调节的利钠肽激素的经典和现代数据。文中呈现了有关多肽种类、其结构、细胞内合成、生理效应以及在模型实验和心血管病理过程中浓度变化的累积数据。讨论了一些尚未解决的问题，包括血浆肽浓度测量方法、它们在心力衰竭发展中的作用及其临床意义。
