Ter Arkh. 2011;83(3):66-74.
Chronic obstructive pulmonary disease (COPD) is a syndrome including a group of obstructive diseases showing both similar features and marked differences. At present, clinicians try to describe various COPD phenotypes reflecting different characteristics of the patients which can be useful in respect of COPD course, prognosis and effective treatment. The article is devoted to approaches to COPD phenotypes definition, gives descriptions of some possible phenotypes and analyses clinical trials of modern COPD treatment modalities in different phenotypes.
慢性阻塞性肺疾病(COPD)是一种综合征,包括一组具有相似特征但又有显著差异的阻塞性疾病。目前,临床医生试图描述反映患者不同特征的各种COPD表型,这对于COPD的病程、预后及有效治疗可能是有用的。本文致力于探讨COPD表型的定义方法,描述一些可能的表型,并分析针对不同表型的现代COPD治疗方式的临床试验。