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伊朗绝经后女性的性功能障碍:患病率及与激素谱的相关性。

Female sexual dysfunction in Iranian postmenopausal women: prevalence and correlation with hormonal profile.

机构信息

Department of Midwifery, Faculty of Nursing & Midwifery, Golestan University of Medical Sciences, Gorgan, Iran.

出版信息

J Sex Med. 2011 Nov;8(11):3154-9. doi: 10.1111/j.1743-6109.2011.02335.x. Epub 2011 Jun 15.

DOI:10.1111/j.1743-6109.2011.02335.x
PMID:21676181
Abstract

INTRODUCTION

Female sexual dysfunction is a current and multifactorial status that greatly affects quality of life. Menopause, aging, and probably hormonal instability are some of these drastic factors.

AIM

Determine the prevalence of sexual dysfunction in Iranian postmenopausal women and the relationship to serum status of sex hormones and sex hormone binding globulin (SHBG).

METHODS

A total of 149 healthy postmenopausal women aged 43-64, nonhormone therapy user, with intact uterus and ovaries, enrolled in the cross-sectional study.

MAIN OUTCOME MEASURES

Female sexual function was evaluated by utilizing the Female Sexual Function Index. Hormonal serum concentration was measured by enzyme-linked Immunosorbent Assay (ELISA). Also, free testosterone and free estradiol indexes were calculated. The analysis was performed by using SPSS 16.

RESULTS

Mean age of sample was 52.19 ± 3.76 with 47.48 ± 36.5 month amenorrhea. In the study, 69.8% of women showed sexual dysfunction in Desire and 61.7% in Arousal, these two being the most affected domains. Lubrication (49.7%), Pain Domain (45.0%), Orgasm (40.3%), and Satisfaction (36.9%) were in later degree among six assessed domains. There was no difference between the two groups-with and without dysfunction-in hormone level and SHBG.

CONCLUSION

In Iranian postmenopausal women, Desire and Arousal are the most prevalent menopausal sexual dysfunctions, and Female Sexual Dysfunction is much more than just a hormonal problem.

摘要

简介

女性性功能障碍是一种当前的、多因素的状态,极大地影响了生活质量。绝经、衰老,可能还有激素不稳定,是其中一些剧烈的因素。

目的

确定伊朗绝经后妇女性功能障碍的流行率,以及与血清性激素和性激素结合球蛋白(SHBG)状态的关系。

方法

共有 149 名年龄在 43-64 岁、未接受激素治疗、子宫和卵巢完整的健康绝经后妇女参与了这项横断面研究。

主要观察指标

利用女性性功能指数评估女性性功能。通过酶联免疫吸附试验(ELISA)测量血清激素浓度。还计算了游离睾酮和游离雌二醇指数。分析采用 SPSS 16 进行。

结果

样本的平均年龄为 52.19 ± 3.76 岁,闭经 47.48 ± 36.5 个月。在研究中,69.8%的女性在欲望方面出现性功能障碍,61.7%在唤起方面出现性功能障碍,这两个方面是受影响最严重的领域。润滑(49.7%)、疼痛领域(45.0%)、高潮(40.3%)和满意度(36.9%)在六个评估领域中处于较低程度。在有和没有性功能障碍的两组之间,激素水平和 SHBG 没有差异。

结论

在伊朗绝经后妇女中,欲望和唤起是最常见的绝经后性功能障碍,女性性功能障碍不仅仅是一个激素问题。

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