Department of Gastroenterology, Medical School, Pontificia Universidad Católica de Chile, Santiago, Chile.
Ann Hepatol. 2011 Jul-Sep;10(3):361-4.
Operational tolerance after liver transplantation has been described in around 20% of the recipients. These patients are able to maintain a normal graft function in the absence of immunosuppressive drugs, thus being free of adverse effects that are common and frequently severe. Here we present a well-documented case of operational tolerance after liver transplantation and discuss current concepts on this topic with emphasis on recent findings that will potentially allow for identifying graft-tolerant patients.
肝移植后约有 20%的受者出现了操作性耐受。这些患者在不使用免疫抑制药物的情况下能够维持正常的移植物功能,从而避免了常见且常严重的不良反应。在此,我们报告了 1 例肝移植后发生操作性耐受的明确病例,并讨论了当前这一主题的概念,重点介绍了可能有助于识别耐受移植物患者的最新发现。