The Institute for Palliative Medicine at San Diego Hospice, San Diego, CA 92103, USA.
Dev Psychobiol. 2011 Jul;53(5):482-8. doi: 10.1002/dev.20558.
This invited address is offered in celebration of the career of Dr. William T. Greenough, especially the mentorship aspect of this illustrious career. It details how glutamate has been a thread throughout my professional career, including in my training with Bill. Our investigations of the role of metabotropic glutamate receptors in synaptic plasticity, specifically in relation to the fragile-X mental retardation protein, are described. I then discuss how glutamate has played a role in my current professional life as a psychiatrist working in palliative care. Finally, I end with some words about how the training I received from Bill has had, and continues to have, an impact on my professional development.
这篇邀请演讲是为了庆祝 William T. Greenough 博士的职业生涯,特别是他杰出职业生涯中的指导方面。它详细介绍了谷氨酸如何贯穿我的职业生涯,包括我与比尔一起接受培训。我们描述了代谢型谷氨酸受体在突触可塑性中的作用的研究,特别是与脆性 X 智力迟钝蛋白的关系。然后,我讨论了谷氨酸在我作为一名从事姑息治疗的精神科医生的当前职业生涯中所扮演的角色。最后,我结束了一些关于我从比尔那里获得的培训对我的专业发展产生的影响,并将继续产生影响的话语。