Prescrire Int. 2011 Jun;20(117):149.
In women with node-negative breast cancer, replacing fluorouracil with docetaxel in the adjuvant chemotherapy protocol did not improve efficacy but in one trial led to a 5-fold increase in serious adverse effects.
在淋巴结阴性的乳腺癌女性患者中,在辅助化疗方案中用多西他赛替代氟尿嘧啶并未提高疗效,但在一项试验中导致严重不良反应增加了5倍。