Department of Dermatology, Venerology and Allergology, Saarland University Hospital, 66421 Homburg, Germany.
Eur J Dermatol. 2011 Jul-Aug;21(4):577-84. doi: 10.1684/ejd.2011.1368.
To evaluate a novel score (HVVSS) for varicose vein patients combining subjective symptoms, clinical findings and functional data of venous insufficiency. 91 patients (118 legs) with primary varicose veins of the great, small or accessory anterior saphenous vein were treated with conventional surgery. HVVSS was assessed pre- and 3 months postoperatively. The data were compared with established clinical and disease-related life quality scores (VCSS, AVVQ, CIVIQ). Test responsiveness, validity and reliability were determined using correlations with CEAP stage and venous refilling time as hemodynamic parameter, and inter-observer variability was assessed. All scores were highly responsive to varicose vein surgery (p<0.001). HVVSS(0-100) decreased from 34.1 ± 13.0 to 9.6 ± 6.9 postoperatively. The relative score change of HVVSS was superior to VCSS (69.5% vs. 58.8%, p=0.005). HVVSS revealed highly significant correlations with the clinical CEAP stage and was exclusively able to differentiate mild from severe disease as defined by venous refilling time (p=0.009). Inter-observer reliability of HVVSS was confirmed by correlation coefficients of 0.977 and 0.950 pre- and postoperatively (p<0.001). HVVSS is a suitable and reliable tool to assess disease severity in varicose vein patients and to quantify therapeutic effects of varicose vein treatment.
评估一种新的评分系统（HVVSS），用于合并静脉功能不全的主观症状、临床发现和功能数据的静脉曲张患者。91 例（118 条肢体）原发性大隐、小隐或副隐前静脉曲张患者行传统手术治疗。在术前和术后 3 个月评估 HVVSS。将数据与既定的临床和与疾病相关的生活质量评分（VCSS、AVVQ、CIVIQ）进行比较。使用与 CEAP 分期和静脉再充盈时间（作为血流动力学参数）的相关性、观察者间变异性来确定测试反应性、有效性和可靠性。所有评分对静脉曲张手术均高度敏感（p<0.001）。HVVSS（0-100）从术前的 34.1 ± 13.0 降至术后的 9.6 ± 6.9。HVVSS 的相对评分变化优于 VCSS（69.5%比 58.8%，p=0.005）。HVVSS 与临床 CEAP 分期高度相关，并且能够单独区分静脉再充盈时间定义的轻度和重度疾病（p=0.009）。术前和术后 HVVSS 的观察者间可靠性通过相关系数 0.977 和 0.950 得到证实（p<0.001）。HVVSS 是评估静脉曲张患者疾病严重程度和量化静脉曲张治疗效果的合适且可靠的工具。
