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头皮巨大毛发母细胞瘤

Giant trichoblastoma of the scalp.

作者信息

Landolsi Amani, Khaled Aida, Bougacha Lobna, Helali Haythem, Kourda Nadia, Fazaa Becima, Zermani Rachida, Kamoun Mohamed Ridha, Adouani Ali

机构信息

Department of Oral Maxillo-facial Surgery, Charles Nicolle Hospital, Tunis, Tunisia.

出版信息

Tunis Med. 2011 Jun;89(6):569-72.

Abstract

BACKGROUND

Trichoblastoma is a rare and benign adnexial tumor with characteristic histological features. It occurs on any hair folliclebearing location, and usually presents as a solitary lesion most often less than 2 cm in size. Giant trichoblastoma has been rarely reported in the literature.

AIM

To report a new case of giant trichoblastoma, misleading for malignancy.

CASE REPORT

A 57-year-old woman presented with a 5 cm-solitary asymptomatic nodular lesion of the scalp, of 28 years. It had been previously excised with recurrence and progressive regrowth. On examination, it was a dome-shaped, erythematous, firm, papillomatous, non infiltrated nodule. Full body work up revealed no metastases. Cutaneous biopsy concluded to trichoblastoma but failed to eliminate malignancy. After excision with secondary skin graft, histological examination confirmed the benignity with clear margins. There was no evidence of recurrence after a 5 year-follow-up period.

CONCLUSION

This case illustrates a rare clinical variant of trichoblastoma with an unusual important size. This can be misleading for malignancy, but the slowly progressive course of the tumour in our patient, together with histological benignity led to the correct diagnosis. This tumour is considered as a distinct entity by some authors.

摘要

背景

毛母细胞瘤是一种罕见的具有特征性组织学特征的良性附属器肿瘤。它发生于任何有毛囊的部位,通常表现为单个病变,大小大多小于2厘米。巨大毛母细胞瘤在文献中鲜有报道。

目的

报告一例易误诊为恶性肿瘤的巨大毛母细胞瘤新病例。

病例报告

一名57岁女性,头皮出现一个5厘米大小的孤立性无症状结节性病变,病程28年。此前曾切除,有复发并逐渐增大。检查发现是一个圆顶状、红斑样、质地硬、乳头状、未浸润的结节。全身检查未发现转移。皮肤活检诊断为毛母细胞瘤,但未能排除恶性肿瘤。二次切除并行皮肤移植后,组织学检查证实为良性且切缘清晰。随访5年无复发迹象。

结论

本病例说明了毛母细胞瘤一种罕见的临床变异型,其大小异常。这可能会误导为恶性肿瘤,但我们患者肿瘤的缓慢进展过程以及组织学良性特征导致了正确的诊断。一些作者认为这种肿瘤是一种独特的实体。

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