Gołab Elzbieta, Rozej-Bielicka Wioletta, Pancer Katarzyna
Department of Medical Parasitology, National Institute of Public Health-National Institute of Hygiene, 24 Chocimska Street, 00-791 Warsaw, Poland.
Wiad Parazytol. 2011;57(2):93-6.
Primary infection with Pneumocystis jirovecii in small children may cause inflammation of the respiratory tract which requires hospitalization. Lack of characteristic clinical symptoms makes it impossible to recognize P. jirovecii infections without performing laboratory analyses. Nasopharyngeal swabs from 70 children with respiratory tract infections were screened for fragments of the P. jirovecii genome. Pneumocystis DNA was found in swabs taken from two (2.9%) of the tested children: a newborn who was infected in the hospital and a six month old baby admitted to hospital two days after pneumonia was diagnosed. The obtained results confirm that primary P. jirovecii infections may occur in the form of acute respiratory tract inflammations suggesting a viral infection. In differential diagnosis of Pneumocystis infections in children molecular methods are useful as their high sensitivity makes it possible to analyze samples obtained in a non-invasive way.
小儿初次感染耶氏肺孢子菌可能会导致呼吸道炎症，这种情况需要住院治疗。由于缺乏特征性临床症状，如果不进行实验室分析，就无法识别耶氏肺孢子菌感染。对70名患有呼吸道感染的儿童的鼻咽拭子进行了耶氏肺孢子菌基因组片段筛查。在两名（2.9%）受试儿童的拭子中发现了肺孢子菌DNA：一名在医院感染的新生儿，以及一名在肺炎确诊两天后入院的6个月大婴儿。所得结果证实，耶氏肺孢子菌原发性感染可能以提示病毒感染的急性呼吸道炎症形式出现。在儿童肺孢子菌感染的鉴别诊断中，分子方法很有用，因为其高灵敏度使得以非侵入性方式获得的样本分析成为可能。
