Health and Rehabilitation Sciences, University of Western Ontario, London, Ontario, Canada.
Clin Neurophysiol. 2012 Jan;123(1):200-5. doi: 10.1016/j.clinph.2011.05.013. Epub 2011 Jun 16.
To collect normative data and assess the intra- and inter-rater reliability of decomposition-enhanced spike-triggered averaging (DE-STA) motor unit number estimation (MUNE) and quantitative MU analysis obtained using decomposition-based quantitative electromyography (DQEMG) in the upper trapezius (UT).
In 10 control subjects, the experimental protocol was performed twice by the same examiner, and once by a second examiner.
Mean MUNE values were 339±121 (rater 1a), 320±131 (rater 1b), and 262±115 (rater 2) MUs. Intra- and inter-rater reliability was good for maximum CMAP (ICC=0.77 and 0.79, respectively) and moderate for MUNE (ICC=0.69 and 0.73, respectively), with poor inter-rater reliability for mean S-MUP (ICC=0.42). Significant differences between rater 1a and 2 were found for mean S-MUP (p=0.014) and MUNE (p=0.002), and moderate to good levels of reliability found for quantitative needle-detected MUP parameters.
Various components of the protocol may have contributed to mean S-MUP variability, and may require particular attention in a large, proximal muscle like the UT.
This study has established preliminary data using DQEMG in a novel muscle which may be relevant to study in patients with ALS.
收集规范数据,并评估基于分解的定量肌电图(DQEMG)中分解增强的尖峰触发平均(DE-STA)运动单位数量估计(MUNE)和定量 MU 分析在上斜方肌(UT)中的内和间评分者可靠性。
在 10 名对照受试者中,同一检查者进行了两次实验方案,第二检查者进行了一次。
平均 MUNE 值为 339±121(评分者 1a)、320±131(评分者 1b)和 262±115(评分者 2)MU。最大 CMAP 的内和间评分者可靠性良好(ICC 分别为 0.77 和 0.79),MUNE 为中度可靠(ICC 分别为 0.69 和 0.73),平均 S-MUP 的间评分者可靠性较差(ICC 为 0.42)。评分者 1a 和 2 之间在平均 S-MUP(p=0.014)和 MUNE(p=0.002)方面存在显著差异,定量针检测 MUP 参数具有中度至良好的可靠性水平。
方案的各个组成部分可能导致平均 S-MUP 变异性,并且在像 UT 这样的大近端肌肉中可能需要特别注意。
本研究使用 DQEMG 在一种新的肌肉中建立了初步数据,这可能与 ALS 患者的研究相关。