Boe Shaun G, Stashuk Daniel W, Doherty Timothy J
School of Kinesiology, The University of Western Ontario, Ont., Canada.
Clin Neurophysiol. 2006 Mar;117(3):596-603. doi: 10.1016/j.clinph.2005.10.021. Epub 2006 Jan 25.
To establish within-subject reliability of motor unit number estimates (MUNEs) and quantitative MU analysis using decomposition-based quantitative electromyography (DQEMG).
Following the acquisition of a maximum M-wave, needle and surface-detected EMG signals were collected during contractions of the first dorsal interrosseous (FDI) and biceps brachii (BB). DQEMG was used to extract motor unit potential (MUP) trains and surface-detected MUPs associated with each train, the mean size of which was divided into the maximum M-wave to obtain a MUNE. Retests were performed following the initial test to evaluate reliability.
Subjects test-retest MUNEs were highly correlated (r=0.72 FDI; 0.97 BB) with no significant differences between test and retest MUNE values (P>0.10). Ninety-five percent confidence intervals were calculated to establish the range of expected retest MUNE variability and were +/-41 MUs for the FDI and BB. Quantitative information pertaining to MU size, complexity and firing rate were similar for both tests.
MUNEs and quantitative MU data can be obtained reliably from the BB and FDI using DQEMG in individual subjects.
Establishing within-subject reliability of MUNEs and quantitative MU analysis allow clinicians to longitudinally follow changes in the MU pool of individuals with disorders of the central or peripheral nervous system in addition to assessing their response to treatments.
利用基于分解的定量肌电图（DQEMG）建立运动单位数量估计（MUNE）和定量运动单位分析的受试者内可靠性。
在获取最大M波后，在第一背侧骨间肌（FDI）和肱二头肌（BB）收缩期间收集针电极和表面检测到的肌电信号。使用DQEMG提取运动单位电位（MUP）序列以及与每个序列相关的表面检测到的MUP，将其平均大小除以最大M波以获得MUNE。在初始测试后进行重新测试以评估可靠性。
受试者的测试 - 重测MUNE高度相关（FDI：r = 0.72；BB：r = 0.97），测试和重测MUNE值之间无显著差异（P>0.10）。计算95%置信区间以确定预期重测MUNE变异性的范围，FDI和BB的范围均为±41个运动单位。两次测试中与运动单位大小、复杂性和放电率相关的定量信息相似。
使用DQEMG可在个体受试者中可靠地从BB和FDI获得MUNE和定量运动单位数据。
建立MUNE的受试者内可靠性和定量运动单位分析，使临床医生除了评估中枢或周围神经系统疾病患者对治疗的反应外，还能够纵向跟踪个体运动单位池的变化。
