Occidental College, USA.
Appetite. 2011 Oct;57(2):397-400. doi: 10.1016/j.appet.2011.06.002. Epub 2011 Jun 12.
The "food addiction" concept implies that proneness to drug dependence and to food dependence should covary. The latter was studied in low- (LoS) and high- (HiS) saccharin-consuming rats, who differ in drug self-administration (HiS>LoS) and withdrawal (LoS>HiS). Sugary food intake in the first 1-2 h was higher in HiS than LoS rats. Sugar intake predicted startle during abstinence only among LoS rats. These results may suggest bingeing-proneness in HiS rats and withdrawal-proneness among LoS rats. However, intake escalation and somatic withdrawal did not differ between lines. Further study with selectively bred rats, with attention to definitions and measures, is warranted.
“食物成瘾”的概念表明，对药物依赖和食物依赖的倾向应该是相互关联的。后者在低（LoS）和高（HiS）糖精消耗大鼠中进行了研究，它们在药物自我给药（HiS>LoS）和戒断（LoS>HiS）方面存在差异。在最初的 1-2 小时内，HiS 大鼠的含糖食物摄入量高于 LoS 大鼠。只有在 LoS 大鼠中，糖摄入量才能预测戒断时的惊跳反应。这些结果可能表明 HiS 大鼠容易暴饮暴食，LoS 大鼠容易戒断。然而，两条线之间的摄入量增加和躯体戒断没有差异。需要进一步研究通过选择性繁殖大鼠，并关注定义和措施。
