Lee Jeffrey H
Department of Gastroenterology, Hepatology, and Nutrition, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1466, Houston, TX 77030-4009, USA.
Gastrointest Endosc Clin N Am. 2011 Jul;21(3):463-80, viii-ix. doi: 10.1016/j.giec.2011.04.009.
Obstructive jaundice can result from benign or malignant etiologies. The common benign conditions include primary sclerosing cholangitis, chronic pancreatitis, and gallstones. Malignant biliary obstruction can be caused by direct tumor infiltration, extrinsic compression by enlarged lymph nodes or malignant lesions, adjacent inflammation, desmoplastic reaction from a tumor, or a combination of these factors. Malignant diseases causing biliary obstruction include pancreatic cancer, ampullary cancer, cholangiocarcinoma, and metastatic diseases. This article focuses on malignant distal biliary obstruction and its management.
梗阻性黄疸可由良性或恶性病因引起。常见的良性疾病包括原发性硬化性胆管炎、慢性胰腺炎和胆结石。恶性胆管梗阻可由肿瘤直接浸润、肿大淋巴结或恶性病变的外在压迫、邻近炎症、肿瘤的促纤维增生反应或这些因素的组合引起。导致胆管梗阻的恶性疾病包括胰腺癌、壶腹癌、胆管癌和转移性疾病。本文重点关注恶性远端胆管梗阻及其治疗。
