Laboratorio de Neuromorfometría, Instituto Nacional de Pediatría, Insurgentes Sur 3700-C, Col. Insurgentes Cuicuilco, Del. Coyoacán, México D.F. 04530, México.
Epilepsy Res. 2011 Sep;96(1-2):166-71. doi: 10.1016/j.eplepsyres.2011.05.017.
In control rats, we examined the effects of ketogenic diet on NKCC1 and KCC2 expression levels in hippocampus. Neither the number of NKCC1 immunoreactive cells nor the intensity of labeling of KCC2 was found to modify in hippocampus of the rats after ketogenic diet treatment. These results indicate that ketogenic diet by itself does not modify the expression of these cation chloride cotransporters.
在对照大鼠中,我们研究了生酮饮食对海马 NKCC1 和 KCC2 表达水平的影响。生酮饮食处理后,大鼠海马中 NKCC1 免疫反应细胞的数量和 KCC2 标记的强度均未发生改变。这些结果表明,生酮饮食本身不会改变这些阳离子-氯离子共转运蛋白的表达。