毛细支气管炎发热婴儿严重细菌感染风险的逐月年龄分析。

Month-by-month age analysis of the risk for serious bacterial infections in febrile infants with bronchiolitis.

作者信息

Yarden-Bilavsky Havatzelet, Ashkenazi-Hoffnung Liat, Livni Gilat, Amir Jacob, Bilavsky Efraim

机构信息

Schneider Children's Medical Center, Petah Tiqva, Israel.

出版信息

Clin Pediatr (Phila). 2011 Nov;50(11):1052-6. doi: 10.1177/0009922811412949. Epub 2011 Jun 17.

DOI:10.1177/0009922811412949

PMID:21685212

Abstract

OBJECTIVE

This study's aim was to assess the risk of serious bacterial infections (SBI) in each of the first 3 months in hospitalizes febrile infants with bronchiolitis.

PATIENTS AND METHODS

The risk of SBI was compared between hospitalized infant with or without bronchiolitis by age in months.

RESULTS

A total of 1125 febrile infants aged ≤3 months were admitted during the study period, 948 without and 177 with bronchiolitis. The incidence of SBI was significantly lower among infants with bronchiolitis compared with those without (4% vs 12.2%, P < .001). However, within the subgroup of neonates with bronchiolitis aged ≤28 days, the incidence of SBI was 9.7% and was not significantly lower than in neonates without bronchiolitis.

CONCLUSION

The risk of SBI among febrile infants with bronchiolitis is significantly lower compared with febrile infants without bronchiolitis, but only after the neonatal period in which the risk for urinary tract infection was relatively high (9.7%).

摘要

目的

本研究旨在评估患细支气管炎的发热住院婴儿在入院后前3个月中每个月发生严重细菌感染（SBI）的风险。

患者与方法

比较不同月龄的患或未患细支气管炎的住院婴儿发生SBI的风险。

结果

在研究期间，共收治了1125名年龄≤3个月的发热婴儿，其中948名未患细支气管炎，177名患细支气管炎。与未患细支气管炎的婴儿相比，患细支气管炎的婴儿中SBI的发生率显著更低（4%对12.2%，P<.001）。然而，在年龄≤28天的患细支气管炎的新生儿亚组中，SBI的发生率为9.7%，并不显著低于未患细支气管炎的新生儿。