Poon Myra, Hussain Khalid
London Centre for Paediatric Endocrinology and Metabolism, Great Ormond Street Hospital for Children NHS Trust, London, UK.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.10.2008.1174. Epub 2009 May 8.
A patient with severe postprandial hyperinsulinaemic hypoglycaemia (PPHH) for 4 years developed type 1 diabetes mellitus. She had no insulin or insulin receptor antibodies but was positive for islet cell and glutamic acid decarboxylase (GAD) antibodies. PPHH prior to the onset of type 1 diabetes mellitus has not been previously described and may be a prodrome of type 1 diabetes mellitus.
一名患有严重餐后高胰岛素血症性低血糖症(PPHH)达4年的患者发展为1型糖尿病。她没有胰岛素或胰岛素受体抗体,但胰岛细胞抗体和谷氨酸脱羧酶(GAD)抗体呈阳性。1型糖尿病发病前出现PPHH的情况此前未见报道,可能是1型糖尿病的前驱症状。