Charalabopoulos Konstantinos, Charalabopoulos Alexandros, Papaioannides Dimitrios
University of Ioannina, Medical Faculty, Department of Physiology, Clinical Unit, 13 Solomou Street, Ioannina, Epirus, 45221, Greece.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.10.2008.1158. Epub 2009 Apr 14.
Insulin dependent diabetes mellitus (IDDM) is considered to be an autoimmune disease. IDDM is associated with other autoimmune diseases such as rheumatoid arthritis, autoimmune thyroid disease, multiple sclerosis, ankylosing spondylitis, psoriasis and systemic lupus erythematosus. Dermatomyositis (DM) is a disease of autoimmune aetiology involving skin and skeletal muscles damaged by an inflammatory process dominated by lymphatic infiltration. The association of IDDM with DM is extraordinarily rare. To our best knowledge, to date only two reports-one of them referring to a patient in childhood-have been published worldwide. DM and IDDM affect children and young adults. Herein, a case of DM in association with IDDM in a 28-year-old man is presented.
胰岛素依赖型糖尿病(IDDM)被认为是一种自身免疫性疾病。IDDM与其他自身免疫性疾病相关,如类风湿性关节炎、自身免疫性甲状腺疾病、多发性硬化症、强直性脊柱炎、牛皮癣和系统性红斑狼疮。皮肌炎(DM)是一种自身免疫病因的疾病,涉及皮肤和骨骼肌,这些组织因以淋巴细胞浸润为主的炎症过程而受损。IDDM与DM的关联极为罕见。据我们所知,迄今为止,全球仅发表了两篇相关报告,其中一篇涉及一名儿童患者。DM和IDDM影响儿童和年轻人。本文报告一例28岁男性患DM合并IDDM的病例。