Kharitonova K I, Rodiukova E N, Simonovich A E, Stupak V V
Zh Vopr Neirokhir Im N N Burdenko. 1990 May-Jun(3):9-11.
Antiseptic gelatin sponges with kanamycin and gentamicin, which were studied in experiments on animals and used in the clinic, are a reliable measure for the prevention of suppuration in craniocerebral surgery in planned operations and in combination with debridement in penetrating injury of the skull and brain. For therapeutic purposes, local application of the agents is effective in focal suppurative processes in the skull and brain after surgical debridement of the purulent focus (abscess of the brain, osteomyelitis of the skull, etc.).
含有卡那霉素和庆大霉素的抗菌明胶海绵,已在动物实验中进行研究并应用于临床,是计划性颅脑手术以及颅骨和脑穿透伤清创术中预防化脓的可靠措施。在治疗方面,在对脓性病灶(脑脓肿、颅骨骨髓炎等)进行手术清创后,将这些药物局部应用于颅骨和脑的局灶性化脓性病变有效。