利妥昔单抗治疗混合型温抗体型与冷抗体型自身免疫性溶血性贫血取得良好疗效。
Good outcome after rituximab treatment for a mixed warm and cold autoimmune haemolytic anaemia.
作者信息
Granel Brigitte, Rossi Pascal, Bernard Fanny, Dettori Isabelle, Costello Regis, Demoux Anne Laurence, Bagneres Denis, Lafforgue Pierre, Frances Yves
机构信息
Hopital Nord, Internal Medicine, Chemin des Bourrely, Marseille, 13915, France.
出版信息
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.09.2008.0857. Epub 2009 Mar 6.
Abstract
Mixed warm and cold autoimmune anaemia is a rare haemolytic anaemia that is commonly associated with lymphoproliferative disorders and autoimmune diseases. Although steroid therapy is the first-line treatment, rituximab represents a good alternative. The present study reports on a successful treatment with rituximab in a young woman suffering from a mixed warm and cold autoimmune haemolytic anaemia associated with a mixed connective tissue disease.
摘要
混合型温抗体与冷抗体自身免疫性贫血是一种罕见的溶血性贫血，通常与淋巴增殖性疾病和自身免疫性疾病相关。尽管类固醇疗法是一线治疗方法，但利妥昔单抗是一种很好的替代方案。本研究报告了一名患有混合型温抗体与冷抗体自身免疫性溶血性贫血并伴有混合性结缔组织病的年轻女性使用利妥昔单抗成功治疗的病例。
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