Perera Mark, Shihana Fatima, Kularathne Keerthi, Dissanayake Damika, Dawson Andrew
SACTRC, Peradeniya, Peradeniya, 091, Sri Lanka.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.07.2008.0515. Epub 2009 Apr 28.
Flower-N is a flowering stimulant composition with 22% nitrobenzene. The main systemic effect associated with human exposure to nitrobenzene is methaemoglobinaemia. A 25-year-old female presented after 3 hours following ingestion of 100 ml of 22% Nitrobenzene (Flower-N). Her initial methaemoglobin (MetHb) was 81%; this responded to methylene blue. However, she developed recurrent methaemoglobinaemia on days 3 and 5 with haemolytic anaemia. The treatments that were provided were repeated methylene blue treatment and exchange transfusion. Nitrobenzene ingestion is a known cause of methaemoglobinaemia and haemolytic anaemia. The recurrence suggests a long half-life. The recurrent MetHb has clinical implications as patients may require repeated treatment. Massive nitrobenzene ingestion can cause haemolysis and recurrent methaemoglobinaemia.
Flower-N是一种含有22%硝基苯的开花刺激剂组合物。人类接触硝基苯的主要全身效应是高铁血红蛋白血症。一名25岁女性在摄入100毫升22%的硝基苯（Flower-N）3小时后就诊。她最初的高铁血红蛋白（MetHb）为81%；这对亚甲蓝有反应。然而，她在第3天和第5天出现了复发性高铁血红蛋白血症并伴有溶血性贫血。所提供的治疗方法是重复使用亚甲蓝治疗和换血疗法。摄入硝基苯是已知的高铁血红蛋白血症和溶血性贫血的病因。复发表明半衰期较长。复发性MetHb具有临床意义，因为患者可能需要反复治疗。大量摄入硝基苯可导致溶血和复发性高铁血红蛋白血症。
