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赞比亚一名开始接受抗逆转录病毒治疗的患者出现急性低磷血症和低钾血症——再喂养综合征的新情况？

Acute hypophosphataemia and hypokalaemia in a patient starting antiretroviral therapy in Zambia-a new context for refeeding syndrome?

作者信息

Nyirenda Christopher, Zulu Isaac, Kabagambe Edmond K, Bagchi Shashwatee, Potter Dara, Bosire Claire, Krishnasami Zipporah, Heimburger Douglas C

机构信息

University Teaching Hospital, Internal Medicine, Ridgeway Campus, Lusaka, N/A, Zambia.

出版信息

BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.07.2008.0469. Epub 2009 Apr 3.

DOI:10.1136/bcr.07.2008.0469
PMID:21686792
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3029658/
Abstract

High mortality rates have been reported in the first 90 days of antiretroviral therapy in Zambia and other low-income countries. We report a case of acute hypophosphataemia and hypokalaemia in the first week of antiretroviral therapy in a patient with extreme AIDS wasting. Given its occurrence in an extremely wasted patient, it may be physiologically similar to refeeding syndrome but other causes could be relevant as well. Acute hypophosphataemia may contribute to early antiretroviral therapy associated mortality in low-income countries.

摘要

据报道，赞比亚和其他低收入国家在抗逆转录病毒治疗的头90天内死亡率很高。我们报告了一例极度消瘦的艾滋病患者在抗逆转录病毒治疗第一周出现急性低磷血症和低钾血症的病例。鉴于其发生在一名极度消瘦的患者身上，其生理情况可能与再喂养综合征相似，但也可能有其他相关原因。急性低磷血症可能导致低收入国家抗逆转录病毒治疗早期死亡率升高。

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