Gołąbek-Dropiewska Katarzyna, Kardel-Reszkewicz Ewelina, Hać Stanisław, Pawłowska Anna, Sledziński Zbigniew
Medical University of Gdañsk, Department of Trauma Surgery, Gdañsk, 80-211, Poland.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.07.2008.0468. Epub 2009 Feb 16.
Gastrointestinal stromal tumour (GIST), within its definition, is a gastrointestinal (GI) mesenchymal tumour containing spindle cells and showing CD 117 immunopositivity. The incidence of GISTs is estimated at 10-20/million. GISTs occur typically in people over 50 years of age. Over 95% of primary GISTs are solitary. Rarely, GISTs are multifocal and occur in young adults and children. A case of a 60-year-old women with double GIST of the stomach is reported here. The patient approached her general practitioner because of stomach ache, chronic diarrhoea and weight loss. Ultrasonography showed an abdominal tumour. During gastroscopy a submucosal tumour in the antral part of the stomach was found. Computed tomography revealed a pathological lesion between the stomach and the liver and an intramural tumour of the stomach. Two stomach tumours were found, and a Bilroth I gastrectomy was performed. Histopathological examination showed GIST in both tumours. This case shows that multifocal GISTs of the stomach can arise in older patients.
胃肠道间质瘤（GIST），根据其定义，是一种胃肠道（GI）间充质肿瘤，包含梭形细胞并显示CD 117免疫阳性。GIST的发病率估计为每百万人口中有10 - 20例。GIST通常发生在50岁以上的人群中。超过95%的原发性GIST是单发的。很少见的是，GIST为多灶性，发生于年轻人和儿童。本文报告一例60岁女性胃双发性GIST病例。该患者因胃痛、慢性腹泻和体重减轻就诊于她的全科医生。超声检查显示腹部有一个肿瘤。胃镜检查时在胃窦部发现一个黏膜下肿瘤。计算机断层扫描显示胃与肝脏之间有一个病理性病变以及胃壁内肿瘤。发现了两个胃肿瘤，并进行了毕罗一世胃切除术。组织病理学检查显示两个肿瘤均为GIST。该病例表明胃多灶性GIST可发生于老年患者。
