英国首次报告的大量A组链球菌败血症及相关水痘感染病例群。
First reported cluster of overwhelming group A streptococcal septicaemia and associated chickenpox infection in the UK.
作者信息
Nyman Andrew Gustaf, Wolfenden Helen, Roy Prem, Morris Jill
机构信息
Milton Keynes General Hospital NHS Trust, Milton Keynes, MK6 5LD, UK.
出版信息
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.06.2008.0028. Epub 2009 Feb 2.
Abstract
We report the first reported cases of epidemiologically linked invasive group A streptococcal septicaemia, with one fatality, following primary chickenpox infection in previously fit and well children who attended the same preschool. Invasive group A streptococcal sepsis is a well documented complication of chickenpox, which requires prompt and aggressive treatment. Following the cluster, public health measures were put in place to prevent further disease. Varicella vaccination has been shown to significantly reduce hospital admissions as well as deaths related to chickenpox infection. This is the first reported cluster of two epidemiologically linked patients in the UK.
摘要
我们报告了首例有流行病学关联的侵袭性A组链球菌败血症病例，一名曾健康的儿童在感染原发性水痘后死亡，这些儿童就读于同一所幼儿园。侵袭性A组链球菌败血症是水痘的一种有充分记录的并发症，需要迅速且积极的治疗。在这起病例群集事件后，采取了公共卫生措施以预防疾病进一步传播。水痘疫苗已被证明能显著减少因水痘感染导致的住院人数和死亡人数。这是英国首次报告的两例有流行病学关联的病例群集事件。
相似文献
1
First reported cluster of overwhelming group A streptococcal septicaemia and associated chickenpox infection in the UK.英国首次报告的大量A组链球菌败血症及相关水痘感染病例群。
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.06.2008.0028. Epub 2009 Feb 2.
2
Invasive group A streptococcal disease in children and association with varicella-zoster virus infection. Ontario Group A Streptococcal Study Group.儿童侵袭性A组链球菌病及其与水痘-带状疱疹病毒感染的关联。安大略省A组链球菌研究小组。
Pediatrics. 2000 May;105(5):E60. doi: 10.1542/peds.105.5.e60.
3
Invasive group A streptococcal infection and nonsteroidal antiinflammatory drug use among children with primary varicella.原发性水痘患儿侵袭性A组链球菌感染与非甾体抗炎药的使用情况
Pediatrics. 2001 May;107(5):1108-15. doi: 10.1542/peds.107.5.1108.
4
Group A streptococcal necrotizing fasciitis after varicella: report of two cases.
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1998 Nov-Dec;39(6):415-8.
5
Severe complications of varicella in previously healthy children in Germany: a 1-year survey.德国既往健康儿童水痘的严重并发症：一项为期1年的调查。
Pediatrics. 2001 Nov;108(5):E79.
6
One dose of varicella vaccine does not prevent school outbreaks: is it time for a second dose?一剂水痘疫苗无法预防学校爆发疫情：是时候接种第二剂了吗？
Pediatrics. 2006 Jun;117(6):e1070-7. doi: 10.1542/peds.2005-2085.
7
Invasive group A streptococcal infections in children with varicella in Southern California.南加州水痘患儿的侵袭性A组链球菌感染
Pediatr Infect Dis J. 1996 Feb;15(2):146-50. doi: 10.1097/00006454-199602000-00011.
8
[Analysis of protective effect of using chickenpox live attenuated vaccine among 4-17 years old children in Minhang district, Shanghai].[上海市闵行区4-17岁儿童水痘减毒活疫苗使用的保护效果分析]
Zhonghua Yu Fang Yi Xue Za Zhi. 2014 Dec;48(12):1048-52.
9
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.在流行地区，服用抗叶酸抗疟药物的人群中，叶酸补充剂与疟疾易感性和严重程度的关系。
Cochrane Database Syst Rev. 2022 Feb 1;2(2022):CD014217. doi: 10.1002/14651858.CD014217.
10
Varicella-associated invasive group A streptococcal disease in Alberta, Canada--2000-2002.加拿大艾伯塔省2000 - 2002年与水痘相关的侵袭性A组链球菌病
Clin Infect Dis. 2005 Apr 1;40(7):1055-7. doi: 10.1086/428614. Epub 2005 Mar 4.
引用本文的文献
1
Varicella infection in a neonate with subsequent staphylococcal scalded skin syndrome and fatal shock.一名新生儿患水痘，随后出现葡萄球菌烫伤样皮肤综合征及致命性休克。
BMJ Case Rep. 2012 Aug 1;2012:bcr2012006462. doi: 10.1136/bcr-2012-006462.
本文引用的文献
1
The epidemiology of severe Streptococcus pyogenes associated disease in Europe.欧洲严重化脓性链球菌相关疾病的流行病学
Euro Surveill. 2005 Sep;10(9):9-10. doi: 10.2807/esm.10.09.00563-en.
2
Varicella vaccine effectiveness in the US vaccination program: a review.美国疫苗接种计划中水痘疫苗的有效性：一项综述。
J Infect Dis. 2008 Mar 1;197 Suppl 2:S82-9. doi: 10.1086/522145.
3
Varicella with stridor: think group A streptococcal epiglottitis.水痘伴喘鸣：考虑A组链球菌性会厌炎。
J Paediatr Child Health. 2008 Mar;44(3):149-51. doi: 10.1111/j.1440-1754.2007.01280.x.
4
Severe complications of chickenpox in hospitalised children in the UK and Ireland.英国和爱尔兰住院儿童水痘的严重并发症
Arch Dis Child. 2007 Dec;92(12):1062-6. doi: 10.1136/adc.2007.123232. Epub 2007 Nov 8.
5
An outbreak of chickenpox at a child care centre in Western Australia. Costs to the community and implications for vaccination policy.西澳大利亚一家儿童保育中心发生水痘疫情。对社区的成本影响及对疫苗接种政策的启示。
Aust N Z J Public Health. 2007 Apr;31(2):113-9. doi: 10.1111/j.1753-6405.2007.00027.x.
6
Varicella.水痘
Lancet. 2006 Oct 14;368(9544):1365-76. doi: 10.1016/S0140-6736(06)69561-5.
7
Interim UK guidelines for management of close community contacts of invasive group A streptococcal disease.英国侵袭性A组链球菌病密切社区接触者管理临时指南。
Commun Dis Public Health. 2004 Dec;7(4):354-61.
8
Prospective surveillance of hospitalisations associated with varicella-zoster virus infections in children and adolescents.对儿童和青少年中与水痘-带状疱疹病毒感染相关的住院情况进行前瞻性监测。
Eur J Pediatr. 2005 Jun;164(6):366-70. doi: 10.1007/s00431-005-1637-8. Epub 2005 Mar 4.
9
Ten year follow-up of healthy children who received one or two injections of varicella vaccine.接受一剂或两剂水痘疫苗的健康儿童的十年随访
Pediatr Infect Dis J. 2004 Feb;23(2):132-7. doi: 10.1097/01.inf.0000109287.97518.67.
10
Invasive group A streptococcal disease in children and association with varicella-zoster virus infection. Ontario Group A Streptococcal Study Group.儿童侵袭性A组链球菌病及其与水痘-带状疱疹病毒感染的关联。安大略省A组链球菌研究小组。
Pediatrics. 2000 May;105(5):E60. doi: 10.1542/peds.105.5.e60.
Zotero 插件