Nyman Andrew Gustaf, Wolfenden Helen, Roy Prem, Morris Jill
Milton Keynes General Hospital NHS Trust, Milton Keynes, MK6 5LD, UK.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.06.2008.0028. Epub 2009 Feb 2.
We report the first reported cases of epidemiologically linked invasive group A streptococcal septicaemia, with one fatality, following primary chickenpox infection in previously fit and well children who attended the same preschool. Invasive group A streptococcal sepsis is a well documented complication of chickenpox, which requires prompt and aggressive treatment. Following the cluster, public health measures were put in place to prevent further disease. Varicella vaccination has been shown to significantly reduce hospital admissions as well as deaths related to chickenpox infection. This is the first reported cluster of two epidemiologically linked patients in the UK.
我们报告了首例有流行病学关联的侵袭性A组链球菌败血症病例，一名曾健康的儿童在感染原发性水痘后死亡，这些儿童就读于同一所幼儿园。侵袭性A组链球菌败血症是水痘的一种有充分记录的并发症，需要迅速且积极的治疗。在这起病例群集事件后，采取了公共卫生措施以预防疾病进一步传播。水痘疫苗已被证明能显著减少因水痘感染导致的住院人数和死亡人数。这是英国首次报告的两例有流行病学关联的病例群集事件。
