Khasakhala L, Sorsdahl K R, Harder V S, Williams D R, Stein D J, Ndetei D M
University of Nairobi, Nairobi, Kenya.
Afr J Psychiatry (Johannesbg). 2011 May;14(2):134-9. doi: 10.4314/ajpsy.v14i2.5.
There is relatively little data on the relationship between lifetime mental disorders and suicidal behaviour in low and middle income countries. This study examines the relationship between lifetime mental disorders, and subsequent suicide ideation, plans, and suicide attempts in South Africa.
A national survey of 4185 South African adults was conducted using the World Health Organization Composite International Diagnostic Interview (CIDI) to generate psychiatric diagnoses and suicidal behaviour. Bivariate, multivariate and discrete-time survival analyses were employed to investigate the associations between mental disorders and subsequent suicide ideation, plans, and attempts.
Sixty-one percent of people who seriously considered killing themselves at some point in their lifetime reported having a prior DSM-IV disorder. Mental disorders predict the onset of suicidal ideation, but have weaker effects in predicting suicide plans or attempts. After controlling for comorbid mental disorders, PTSD was the strongest predictor of suicidal ideation and attempts. There is a relationship between number of mental disorders and suicidal behaviour, with comorbidity having significantly sub-additive effects.
Consistent with data from the developed world, mental disorders are strong predictors of suicidal behaviour, and these associations are more often explained by the prediction of ideation, rather than the prediction of attempts amongst ideators. This suggests some universality of the relevant mechanisms underlying the genesis of suicidal thoughts, and the progression to suicide attempts.
在低收入和中等收入国家,关于终生精神障碍与自杀行为之间关系的数据相对较少。本研究考察了南非终生精神障碍与随后的自杀意念、计划及自杀未遂之间的关系。
采用世界卫生组织综合国际诊断访谈(CIDI)对4185名南非成年人进行全国性调查,以得出精神疾病诊断和自杀行为。采用双变量、多变量和离散时间生存分析来研究精神障碍与随后的自杀意念、计划及未遂之间的关联。
在一生中曾在某个时刻认真考虑过自杀的人当中,61%报告曾患有先前的DSM-IV障碍。精神障碍可预测自杀意念的出现,但在预测自杀计划或未遂方面作用较弱。在控制了共病精神障碍后,创伤后应激障碍是自杀意念和未遂的最强预测因素。精神障碍的数量与自杀行为之间存在关联,共病具有显著的次相加效应。
与发达国家的数据一致,精神障碍是自杀行为的有力预测因素,这些关联更多是通过对意念的预测来解释,而非对有自杀意念者的未遂行为的预测。这表明自杀念头产生及发展为自杀未遂背后的相关机制具有某种普遍性。