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Mental disorders, comorbidity and suicidal behavior: results from the National Comorbidity Survey Replication.精神障碍、共病和自杀行为:来自国家共病调查再调查的结果。
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Non-fatal suicidal behavior among South Africans : results from the South Africa Stress and Health Study.南非人的非致命自杀行为:来自南非压力与健康研究的结果
Soc Psychiatry Psychiatr Epidemiol. 2008 Jun;43(6):454-61. doi: 10.1007/s00127-008-0348-7. Epub 2008 May 12.
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Lifetime prevalence of psychiatric disorders in South Africa.南非精神疾病的终生患病率。
Br J Psychiatry. 2008 Feb;192(2):112-7. doi: 10.1192/bjp.bp.106.029280.
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Cross-national prevalence and risk factors for suicidal ideation, plans and attempts.自杀意念、计划和企图的跨国患病率及风险因素。
Br J Psychiatry. 2008 Feb;192(2):98-105. doi: 10.1192/bjp.bp.107.040113.
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Risk factors for the incidence and persistence of suicide-related outcomes: a 10-year follow-up study using the National Comorbidity Surveys.自杀相关结局的发生率和持续存在的风险因素:一项使用国家共病调查的10年随访研究。
J Affect Disord. 2008 Jan;105(1-3):25-33. doi: 10.1016/j.jad.2007.01.036. Epub 2007 May 16.
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Suicide prevention: the urgent need in developing countries.自杀预防:发展中国家的迫切需求。
World Psychiatry. 2004 Oct;3(3):158-9.
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Trends in suicide ideation, plans, gestures, and attempts in the United States, 1990-1992 to 2001-2003.1990 - 1992年至2001 - 2003年美国自杀意念、计划、未遂行为及自杀未遂情况的趋势
JAMA. 2005 May 25;293(20):2487-95. doi: 10.1001/jama.293.20.2487.
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Profile of suicide in Dar es Salaam.达累斯萨拉姆的自杀概况。
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Suicide risk in relation to psychiatric hospitalization: evidence based on longitudinal registers.与精神科住院治疗相关的自杀风险:基于纵向登记册的证据
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Posttraumatic stress disorder comorbid with major depression: factors mediating the association with suicidal behavior.创伤后应激障碍合并重度抑郁症:介导与自杀行为关联的因素。
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南非的终生精神障碍与自杀行为

Lifetime mental disorders and suicidal behaviour in South Africa.

作者信息

Khasakhala L, Sorsdahl K R, Harder V S, Williams D R, Stein D J, Ndetei D M

机构信息

University of Nairobi, Nairobi, Kenya.

出版信息

Afr J Psychiatry (Johannesbg). 2011 May;14(2):134-9. doi: 10.4314/ajpsy.v14i2.5.

DOI:10.4314/ajpsy.v14i2.5
PMID:21687912
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3224178/
Abstract

OBJECTIVE

There is relatively little data on the relationship between lifetime mental disorders and suicidal behaviour in low and middle income countries. This study examines the relationship between lifetime mental disorders, and subsequent suicide ideation, plans, and suicide attempts in South Africa.

METHOD

A national survey of 4185 South African adults was conducted using the World Health Organization Composite International Diagnostic Interview (CIDI) to generate psychiatric diagnoses and suicidal behaviour. Bivariate, multivariate and discrete-time survival analyses were employed to investigate the associations between mental disorders and subsequent suicide ideation, plans, and attempts.

RESULTS

Sixty-one percent of people who seriously considered killing themselves at some point in their lifetime reported having a prior DSM-IV disorder. Mental disorders predict the onset of suicidal ideation, but have weaker effects in predicting suicide plans or attempts. After controlling for comorbid mental disorders, PTSD was the strongest predictor of suicidal ideation and attempts. There is a relationship between number of mental disorders and suicidal behaviour, with comorbidity having significantly sub-additive effects.

CONCLUSION

Consistent with data from the developed world, mental disorders are strong predictors of suicidal behaviour, and these associations are more often explained by the prediction of ideation, rather than the prediction of attempts amongst ideators. This suggests some universality of the relevant mechanisms underlying the genesis of suicidal thoughts, and the progression to suicide attempts.

摘要

目的

在低收入和中等收入国家,关于终生精神障碍与自杀行为之间关系的数据相对较少。本研究考察了南非终生精神障碍与随后的自杀意念、计划及自杀未遂之间的关系。

方法

采用世界卫生组织综合国际诊断访谈(CIDI)对4185名南非成年人进行全国性调查,以得出精神疾病诊断和自杀行为。采用双变量、多变量和离散时间生存分析来研究精神障碍与随后的自杀意念、计划及未遂之间的关联。

结果

在一生中曾在某个时刻认真考虑过自杀的人当中,61%报告曾患有先前的DSM-IV障碍。精神障碍可预测自杀意念的出现,但在预测自杀计划或未遂方面作用较弱。在控制了共病精神障碍后,创伤后应激障碍是自杀意念和未遂的最强预测因素。精神障碍的数量与自杀行为之间存在关联,共病具有显著的次相加效应。

结论

与发达国家的数据一致,精神障碍是自杀行为的有力预测因素,这些关联更多是通过对意念的预测来解释,而非对有自杀意念者的未遂行为的预测。这表明自杀念头产生及发展为自杀未遂背后的相关机制具有某种普遍性。