Department of Clinical Neurosciences, Institute of Neurology, University College London, Royal Free Campus, London, UK.
J Neurol Sci. 2011 Nov 15;310(1-2):216-9. doi: 10.1016/j.jns.2011.05.045.
The choice of a scale has important implications for the results of clinical research, including epidemiological and treatment studies. In addition to the requirements for any clinical scale, evaluation of rating scales for depression and apathy in Parkinson's disease (PD) faces additional challenges, reflecting the overlap of syndromes, controversies on the concept particularly of apathy, fluctuations related to medication, and difficulties in assessment. However, a number of rating scales are available which have been assessed for use in patients with PD, and the evidence for the use of these scales is discussed. A number of scales fulfil the basic requirements but further studies on their properties are required. Scales for screening need to have different properties than scales for rating severity. Overall, there is no perfect scale, but the choice of scale needs to take into account clinimetric properties, validity in the sample examined, content and purpose.
量表的选择对临床研究结果有重要影响，包括流行病学和治疗研究。除了对任何临床量表的要求外，评估帕金森病（PD）患者的抑郁和淡漠评定量表还面临着额外的挑战，反映了综合征的重叠、特别是淡漠概念上的争议、与药物相关的波动以及评估的困难。然而，有许多已被评估用于 PD 患者的评定量表，本文讨论了这些量表的应用证据。一些量表满足了基本要求，但需要进一步研究其特性。用于筛查的量表需要具有与严重程度评定量表不同的特性。总的来说，没有完美的量表，但量表的选择需要考虑计量特性、在检查样本中的有效性、内容和目的。
