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乙琥胺致 10 岁男孩躁狂。

Ethosuximide-induced mania in a 10-year-old boy.

机构信息

Division of Child and Adolescent Psychiatry, Department of Psychiatry, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA.

出版信息

Epilepsy Behav. 2011 Aug;21(4):483-5. doi: 10.1016/j.yebeh.2011.05.004.

DOI:10.1016/j.yebeh.2011.05.004
PMID:21689989
Abstract

Psychosis and suicidal ideation have been reported as side effects of ethosuximide treatment, but previous reports seldom place these symptoms in the context of mania. Given the recent renewed interest in ethosuximide as first-line therapy in children and adolescents, it is important for clinicians to be aware of the potential psychiatric complication of mania with this medication. Described here is the case of a 10-year-old boy who developed acute mania, as well as psychotic symptoms and suicidal ideation, on ethosuximide.

摘要

精神病和自杀意念已被报道为乙琥胺治疗的副作用,但以前的报告很少将这些症状置于躁狂症的背景下。鉴于最近重新关注乙琥胺作为儿童和青少年的一线治疗药物,临床医生了解这种药物引起躁狂的潜在精神并发症非常重要。这里描述的是一名 10 岁男孩在服用乙琥胺后出现急性躁狂、精神病症状和自杀意念的病例。

相似文献

1
Ethosuximide-induced mania in a 10-year-old boy.乙琥胺致 10 岁男孩躁狂。
Epilepsy Behav. 2011 Aug;21(4):483-5. doi: 10.1016/j.yebeh.2011.05.004.
2
Mania and anticonvulsant therapy.躁狂症与抗惊厥治疗
J Am Acad Child Adolesc Psychiatry. 1995 Jun;34(6):699. doi: 10.1097/00004583-199506000-00001.
3
Mania and anticonvulsant therapy.躁狂症与抗惊厥治疗。
J Am Acad Child Adolesc Psychiatry. 1992 Nov;31(6):1168. doi: 10.1097/00004583-199211000-00032.
4
[Psychiatric and psychologic effects of ethosuximide treatment of epileptics].乙琥胺治疗癫痫患者的精神和心理效应
Encephale. 1968 Sep-Oct;57(5):407-38.
5
[Possibility for provoking grand mal series in ethosuximide therapy--2 case reports].[乙琥胺治疗中诱发癫痫大发作连续状态的可能性——2例报告]
Psychiatr Neurol Med Psychol (Leipz). 1990 Sep;42(9):576-7.
6
Use of ethosuximide and valproate in the treatment of epilepsy.乙琥胺和丙戊酸盐在癫痫治疗中的应用。
Neurol Clin. 1986 Aug;4(3):601-16.
7
[Ethosuximide in treatment of petit mal epilepsy].乙琥胺治疗失神性癫痫
No To Shinkei. 1965 Aug;17(8):831-40.
8
[Clinical trials with ethosuximide (Zarontin) in therapy-resistant epileptics].[乙琥胺(柴郎丁)治疗难治性癫痫患者的临床试验]
No To Shinkei. 1965 Sep;17(9):958-64.
9
Once-daily ethosuximide in the treatment of absence epilepsy.每日一次服用乙琥胺治疗失神性癫痫。
Pediatr Neurol. 1990 Jan-Feb;6(1):38-9. doi: 10.1016/0887-8994(90)90076-d.
10
Forced normalization induced by ethosuximide therapy in a patient with intractable myoclonic epilepsy.乙琥胺治疗难治性肌阵挛性癫痫患者引发的强制性正常化。
Brain Dev. 2001 Mar;23(1):62-4. doi: 10.1016/s0387-7604(01)00177-2.

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The Black Book of Psychotropic Dosing and Monitoring.《精神药物剂量与监测黑皮书》
Psychopharmacol Bull. 2018 Jan 15;48(1):64-153.
2
Epilepsy, Antiepileptic Drugs, and Aggression: An Evidence-Based Review.癫痫、抗癫痫药物与攻击性:一项基于证据的综述。
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