ACP Journal Club. Candesartan did not improve clinical or functional outcomes in patients with acute stroke and elevated BP.
作者信息
Frieden Rick
机构信息
Lakeland Regional Health System, St. Joseph, MI, USA.
出版信息
Ann Intern Med. 2011 Jun 21;154(12):JC6-5. doi: 10.7326/0003-4819-154-12-201106210-02005.
Abstract
摘要
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ACP Journal Club. Candesartan did not improve clinical or functional outcomes in patients with acute stroke and elevated BP.《美国医师协会杂志俱乐部》。坎地沙坦对急性中风且血压升高的患者的临床或功能结局并无改善作用。
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Hypertension after experimental cerebral ischemia: candesartan provides neurovascular protection.实验性脑缺血后的高血压：坎地沙坦提供神经血管保护。
J Hypertens. 2006 Mar;24(3):535-9. doi: 10.1097/01.hjh.0000209990.41304.43.
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ACP Journal Club. Adding niacin to simvastatin did not improve clinical outcomes in patients with CV disease and dyslipidemia.《美国内科医师学会杂志俱乐部》。在患有心血管疾病和血脂异常的患者中，将烟酸添加到辛伐他汀中并不能改善临床结局。
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Vascular protection with candesartan after experimental acute stroke in hypertensive rats: a dose-response study.坎地沙坦对高血压大鼠实验性急性卒中后的血管保护作用：一项剂量反应研究。
J Pharmacol Exp Ther. 2008 Sep;326(3):773-82. doi: 10.1124/jpet.108.139618. Epub 2008 Jun 17.
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Renin-angiotensin system blockade safely reduces blood pressure in patients with minor ischemic stroke during the acute phase.肾素-血管紧张素系统阻断剂在急性缺血性小卒中患者中安全降压。
J Stroke Cerebrovasc Dis. 2010 Nov-Dec;19(6):435-40. doi: 10.1016/j.jstrokecerebrovasdis.2009.08.006. Epub 2010 Aug 11.
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ACP Journal Club: adding renal dysfunction to CHADS2 did not improve prediction of stroke or systemic embolism in AF.《美国内科医师学会杂志俱乐部》：在CHADS2评分中加入肾功能不全并不能改善对房颤患者中风或全身性栓塞的预测。
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