Knispel H, Dieckmann K P, Henze G, Loy V
Urologische Klinik, FU Berlin im Klinikum Steglitz.
Urologe A. 1990 Jul;29(4):226-9; discussion 213-4.
A rare case of metastatic nephroblastoma on the right side in a 28-year-old female patient is presented. Complete remission was achieved by inductive chemotherapy with vincristine, Adriamycin, actinomycin D and cyclophosphamide and subsequent radical nephrectomy. There was no evidence of disease 24 months after the initial diagnosis had been made. The problems specific to the diagnosis and treatment of adult Wilms tumor are discussed. A chemotherapy regimen known to be successful in childhood Wilms tumor was shown to be equally effective in our adult patient.
本文报告了一例28岁女性患者右侧转移性肾母细胞瘤的罕见病例。通过长春新碱、阿霉素、放线菌素D和环磷酰胺诱导化疗及随后的根治性肾切除术实现了完全缓解。初次诊断后24个月无疾病证据。讨论了成人肾母细胞瘤诊断和治疗的特殊问题。已知在儿童肾母细胞瘤中成功的化疗方案在我们的成年患者中同样有效。