Kobe City College of Technology, Kobe, Japan.
Phys Med Biol. 2011 Jul 7;56(13):4147-59. doi: 10.1088/0031-9155/56/13/026. Epub 2011 Jun 21.
The silicon-photomultiplier (Si-PM) is a promising photodetector, especially for integrated PET/MRI systems, due to its small size, high gain, and low sensitivity to static magnetic fields. The major problem using a Si-PM-based PET system within the MRI system is the interference between the PET and MRI units. We measured the interference by combining a Si-PM-based PET system with a permanent-magnet MRI system. When the RF signal-induced pulse height exceeded the lower energy threshold level of the PET system, interference between the Si-PM-based PET system and MRI system was detected. The prompt as well as the delayed coincidence count rates of the Si-PM-based PET system increased significantly. These noise counts produced severe artifacts on the reconstructed images of the Si-PM-based PET system. In terms of the effect of the Si-PM-based PET system on the MRI system, although no susceptibility artifact was observed on the MR images, electronic noise from the PET detector ring was detected by the RF coil and reduced the signal-to-noise ratio (S/N) of the MR images. The S/N degradation of the MR images was reduced when the distance between the RF coil and the Si-PM-based PET system was increased. We conclude that reducing the interference between the PET and MRI systems is essential for achieving the optimum performance of integrated Si-PM PET/MRI systems.
硅光电倍增管(Si-PM)是一种很有前途的光电探测器,特别是对于集成的 PET/MRI 系统来说,因为它体积小、增益高、对静磁场的敏感度低。在 MRI 系统中使用基于 Si-PM 的 PET 系统的主要问题是 PET 和 MRI 单元之间的干扰。我们通过将基于 Si-PM 的 PET 系统与永磁 MRI 系统相结合来测量这种干扰。当 RF 信号诱导的脉冲高度超过 PET 系统的较低能量阈值水平时,就会检测到基于 Si-PM 的 PET 系统和 MRI 系统之间的干扰。基于 Si-PM 的 PET 系统的快速和延迟符合计数率显著增加。这些噪声计数会在基于 Si-PM 的 PET 系统的重建图像上产生严重的伪影。就基于 Si-PM 的 PET 系统对 MRI 系统的影响而言,尽管在 MR 图像上没有观察到磁化率伪影,但从 PET 探测器环发出的电子噪声被 RF 线圈检测到,并降低了 MR 图像的信噪比(S/N)。当增加 RF 线圈和基于 Si-PM 的 PET 系统之间的距离时,MR 图像的 S/N 降低得到了缓解。我们得出结论,减少 PET 和 MRI 系统之间的干扰对于实现集成 Si-PM PET/MRI 系统的最佳性能至关重要。